Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory study
Purpose: Physical activity (PA) is an important determinant of skeletal health. In young adults with type 1 diabetes (T1D) fracture risk is increased, yet few studies have examined the PA and bone health relationship. Therefore, this pilot cross-sectional study characterized PA levels and their asso...
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| Language: | English |
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Elsevier
2024-12-01
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| Series: | Bone Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352187224000809 |
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| author | Sarah L. West Michelle Furman Rahim Moineddin Etienne Sochett |
| author_facet | Sarah L. West Michelle Furman Rahim Moineddin Etienne Sochett |
| author_sort | Sarah L. West |
| collection | DOAJ |
| description | Purpose: Physical activity (PA) is an important determinant of skeletal health. In young adults with type 1 diabetes (T1D) fracture risk is increased, yet few studies have examined the PA and bone health relationship. Therefore, this pilot cross-sectional study characterized PA levels and their association with bone parameters measured by high resolution peripheral quantitative computed tomography (HR-pQCT) in young adults with T1D. Methods: HR-pQCT (Xtreme CTII) was used to measure bone outcomes at the distal tibia and radius, and accelerometery (ActiGraph GT3X) recorded daily minutes of light and moderate-vigorous physical activity (MVPA). Quadratic regression analyses were conducted with a p-value ≤ 0.05 considered significant. Results: PA data from 19 young adults (23.1 ± 1.9 years) with T1D was analyzed. Over half (63 %) of participants completed ≥150 min of MVPA per week, however, most measured activity time per day (57 %) was spent in sedentary pursuits. Significant non-linear associations were found between the duration of MVPA and several trabecular bone parameters at the tibia. Conclusions: In young adults with T1D, MVPA may have site specific (tibia) and compartment specific (trabecular) non-linear associations with bone. Further studies should confirm these findings, which may help inform evidence-based exercise recommendations to optimize bone health in young adults with T1D. |
| format | Article |
| id | doaj-art-96ccded02d294b9a9284b55213a1beed |
| institution | Kabale University |
| issn | 2352-1872 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Bone Reports |
| spelling | doaj-art-96ccded02d294b9a9284b55213a1beed2024-11-27T05:02:48ZengElsevierBone Reports2352-18722024-12-0123101813Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory studySarah L. West0Michelle Furman1Rahim Moineddin2Etienne Sochett3Department of Kinesiology, Trent University, Peterborough, ON, Canada; Corresponding author at: Department of Kinesiology, ESB C105, Trent University, Peterborough, ON K9L 0G2, Canada.Department of Pediatrics, Division of Endocrinology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, CanadaDepartment of Family and Community Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, CanadaDepartment of Pediatrics, Division of Endocrinology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, CanadaPurpose: Physical activity (PA) is an important determinant of skeletal health. In young adults with type 1 diabetes (T1D) fracture risk is increased, yet few studies have examined the PA and bone health relationship. Therefore, this pilot cross-sectional study characterized PA levels and their association with bone parameters measured by high resolution peripheral quantitative computed tomography (HR-pQCT) in young adults with T1D. Methods: HR-pQCT (Xtreme CTII) was used to measure bone outcomes at the distal tibia and radius, and accelerometery (ActiGraph GT3X) recorded daily minutes of light and moderate-vigorous physical activity (MVPA). Quadratic regression analyses were conducted with a p-value ≤ 0.05 considered significant. Results: PA data from 19 young adults (23.1 ± 1.9 years) with T1D was analyzed. Over half (63 %) of participants completed ≥150 min of MVPA per week, however, most measured activity time per day (57 %) was spent in sedentary pursuits. Significant non-linear associations were found between the duration of MVPA and several trabecular bone parameters at the tibia. Conclusions: In young adults with T1D, MVPA may have site specific (tibia) and compartment specific (trabecular) non-linear associations with bone. Further studies should confirm these findings, which may help inform evidence-based exercise recommendations to optimize bone health in young adults with T1D.http://www.sciencedirect.com/science/article/pii/S2352187224000809Type 1 diabetesYoung adultsPhysical activityHR-pQCTAccelerometry |
| spellingShingle | Sarah L. West Michelle Furman Rahim Moineddin Etienne Sochett Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory study Bone Reports Type 1 diabetes Young adults Physical activity HR-pQCT Accelerometry |
| title | Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory study |
| title_full | Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory study |
| title_fullStr | Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory study |
| title_full_unstemmed | Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory study |
| title_short | Association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes — A pilot exploratory study |
| title_sort | association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes a pilot exploratory study |
| topic | Type 1 diabetes Young adults Physical activity HR-pQCT Accelerometry |
| url | http://www.sciencedirect.com/science/article/pii/S2352187224000809 |
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