Functional dyspepsia and gut microbiome
The definitive pathophysiology of functional dyspepsia remains unclear, and effective treatments are limited. Among the mechanisms assumed to be involved in its pathogenesis, duodenal low-grade inflammation has received the most attention. Emerging evidence suggests that the oral microbiome, such as...
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Language: | English |
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Verduci Editore
2024-10-01
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Series: | Microbiota in Health and Disease |
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Online Access: | https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/10/e1096.pdf |
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author | H. Mori M. Sano H. Suzuki |
author_facet | H. Mori M. Sano H. Suzuki |
author_sort | H. Mori |
collection | DOAJ |
description | The definitive pathophysiology of functional dyspepsia remains unclear, and effective treatments are limited. Among the mechanisms assumed to be involved in its pathogenesis, duodenal low-grade inflammation has received the most attention. Emerging evidence suggests that the oral microbiome, such as Streptococcus spp., may play a role in gastroduodenal motility and low-grade duodenal inflammation. In terms of treatment, traditional treatments, such as herbal medicine, are showing changes in the intestinal microbiome and its metabolites. In other words, both old and new evidence are being progressively revealed. |
format | Article |
id | doaj-art-96b8a9b6092b452da94f643e223065b6 |
institution | Kabale University |
issn | 2704-8845 |
language | English |
publishDate | 2024-10-01 |
publisher | Verduci Editore |
record_format | Article |
series | Microbiota in Health and Disease |
spelling | doaj-art-96b8a9b6092b452da94f643e223065b62025-01-03T10:30:12ZengVerduci EditoreMicrobiota in Health and Disease2704-88452024-10-01610.26355/mhd_202410_10961096Functional dyspepsia and gut microbiomeH. Mori0M. Sano1H. Suzuki2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, JapanThe definitive pathophysiology of functional dyspepsia remains unclear, and effective treatments are limited. Among the mechanisms assumed to be involved in its pathogenesis, duodenal low-grade inflammation has received the most attention. Emerging evidence suggests that the oral microbiome, such as Streptococcus spp., may play a role in gastroduodenal motility and low-grade duodenal inflammation. In terms of treatment, traditional treatments, such as herbal medicine, are showing changes in the intestinal microbiome and its metabolites. In other words, both old and new evidence are being progressively revealed.https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/10/e1096.pdffunctional dyspepsiamicrobiomelow-grade inflammationstomachduodenum. |
spellingShingle | H. Mori M. Sano H. Suzuki Functional dyspepsia and gut microbiome Microbiota in Health and Disease functional dyspepsia microbiome low-grade inflammation stomach duodenum. |
title | Functional dyspepsia and gut microbiome |
title_full | Functional dyspepsia and gut microbiome |
title_fullStr | Functional dyspepsia and gut microbiome |
title_full_unstemmed | Functional dyspepsia and gut microbiome |
title_short | Functional dyspepsia and gut microbiome |
title_sort | functional dyspepsia and gut microbiome |
topic | functional dyspepsia microbiome low-grade inflammation stomach duodenum. |
url | https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/10/e1096.pdf |
work_keys_str_mv | AT hmori functionaldyspepsiaandgutmicrobiome AT msano functionaldyspepsiaandgutmicrobiome AT hsuzuki functionaldyspepsiaandgutmicrobiome |