Functional dyspepsia and gut microbiome

The definitive pathophysiology of functional dyspepsia remains unclear, and effective treatments are limited. Among the mechanisms assumed to be involved in its pathogenesis, duodenal low-grade inflammation has received the most attention. Emerging evidence suggests that the oral microbiome, such as...

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Main Authors: H. Mori, M. Sano, H. Suzuki
Format: Article
Language:English
Published: Verduci Editore 2024-10-01
Series:Microbiota in Health and Disease
Subjects:
Online Access:https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/10/e1096.pdf
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author H. Mori
M. Sano
H. Suzuki
author_facet H. Mori
M. Sano
H. Suzuki
author_sort H. Mori
collection DOAJ
description The definitive pathophysiology of functional dyspepsia remains unclear, and effective treatments are limited. Among the mechanisms assumed to be involved in its pathogenesis, duodenal low-grade inflammation has received the most attention. Emerging evidence suggests that the oral microbiome, such as Streptococcus spp., may play a role in gastroduodenal motility and low-grade duodenal inflammation. In terms of treatment, traditional treatments, such as herbal medicine, are showing changes in the intestinal microbiome and its metabolites. In other words, both old and new evidence are being progressively revealed.
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institution Kabale University
issn 2704-8845
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series Microbiota in Health and Disease
spelling doaj-art-96b8a9b6092b452da94f643e223065b62025-01-03T10:30:12ZengVerduci EditoreMicrobiota in Health and Disease2704-88452024-10-01610.26355/mhd_202410_10961096Functional dyspepsia and gut microbiomeH. Mori0M. Sano1H. Suzuki2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, JapanThe definitive pathophysiology of functional dyspepsia remains unclear, and effective treatments are limited. Among the mechanisms assumed to be involved in its pathogenesis, duodenal low-grade inflammation has received the most attention. Emerging evidence suggests that the oral microbiome, such as Streptococcus spp., may play a role in gastroduodenal motility and low-grade duodenal inflammation. In terms of treatment, traditional treatments, such as herbal medicine, are showing changes in the intestinal microbiome and its metabolites. In other words, both old and new evidence are being progressively revealed.https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/10/e1096.pdffunctional dyspepsiamicrobiomelow-grade inflammationstomachduodenum.
spellingShingle H. Mori
M. Sano
H. Suzuki
Functional dyspepsia and gut microbiome
Microbiota in Health and Disease
functional dyspepsia
microbiome
low-grade inflammation
stomach
duodenum.
title Functional dyspepsia and gut microbiome
title_full Functional dyspepsia and gut microbiome
title_fullStr Functional dyspepsia and gut microbiome
title_full_unstemmed Functional dyspepsia and gut microbiome
title_short Functional dyspepsia and gut microbiome
title_sort functional dyspepsia and gut microbiome
topic functional dyspepsia
microbiome
low-grade inflammation
stomach
duodenum.
url https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/10/e1096.pdf
work_keys_str_mv AT hmori functionaldyspepsiaandgutmicrobiome
AT msano functionaldyspepsiaandgutmicrobiome
AT hsuzuki functionaldyspepsiaandgutmicrobiome