Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning

Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning

Abstract Recent advances in spatial transcriptomics have enabled simultaneous preservation of high‐throughput gene expression profiles and the spatial context, enabling high‐resolution exploration of distinct regional characterization in tissue. To effectively understand the underlying biological me...

Full description

Saved in:

Bibliographic Details
Main Authors:	Zhuohan Yu, Yuning Yang, Xingjian Chen, Ka‐Chun Wong, Zhaolei Zhang, Yuming Zhao, Xiangtao Li
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Series:	Advanced Science
Subjects:	dual graph contrastive learning gene regulation graph contrastive learning spatial heterogeneity
Online Access:	https://doi.org/10.1002/advs.202410081
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Rethinking spatial-temporal contrastive learning for Urban traffic flow forecasting: multi-level augmentation framework
by: Lin Pan, et al.
Published: (2024-12-01)

A temporal knowledge graph reasoning model based on recurrent encoding and contrastive learning
by: Weitong Liu, et al.
Published: (2025-01-01)

Towards accurate anomaly detection for cloud system via graph-enhanced contrastive learning
by: Zhen Zhang, et al.
Published: (2024-11-01)

Data augmentation based multi-view contrastive learning graph anomaly detection
by: LI Yifan, et al.
Published: (2024-10-01)

Sequential recommendation algorithm for long-tail users based on knowledge-enhanced contrastive learning
by: REN Yonggong, et al.
Published: (2024-06-01)

Predicting noncoding RNA and disease associations using multigraph contrastive learning
by: Si-Lin Sun, et al.
Published: (2025-01-01)

CLB-Defense: based on contrastive learning defense for graph neural network against backdoor attack
by: Jinyin CHEN, et al.
Published: (2023-04-01)

Drug-Gene Interaction Prediction Method through Cross Granularity Subgraph Contrastive Learning and Attention Mechanism Fusion
by: HU Dongdong, et al.
Published: (2025-01-01)

A Social Media Dataset and H-GNN-Based Contrastive Learning Scheme for Multimodal Sentiment Analysis
by: Jiao Peng, et al.
Published: (2025-01-01)

Multi-channel spatio-temporal graph attention contrastive network for brain disease diagnosis
by: Chaojun Li, et al.
Published: (2025-02-01)

SGCL-LncLoc: An Interpretable Deep Learning Model for Improving lncRNA Subcellular Localization Prediction with Supervised Graph Contrastive Learning
by: Min Li, et al.
Published: (2024-09-01)

Hyperbolic Graph Convolutional Network Relation Extraction Model Combining Dependency Syntax and Contrastive Learning
by: Jinzhe Li
Published: (2025-02-01)

Hierarchical Contrastive Representation for Accurate Evaluation of Rehabilitation Exercises via Multi-View Skeletal Representations
by: Zhejun Kuang, et al.
Published: (2025-01-01)

DMR: disentangled and denoised learning for multi-behavior recommendation
by: Yijia Zhang, et al.
Published: (2025-01-01)

CDPMF-DDA: contrastive deep probabilistic matrix factorization for drug-disease association prediction
by: Xianfang Tang, et al.
Published: (2025-01-01)

English-Polish contrastive grammar at Polish universities
by: Elżbieta Mańczak-Wohlfeld
Published: (2016-12-01)

CoGraphNet for enhanced text classification using word-sentence heterogeneous graph representations and improved interpretability
by: Pengyi Li, et al.
Published: (2025-01-01)

Contrastive Markers in Contrast
by: Maria Josep Cuenca, et al.
Published: (2019-12-01)

Evaluatıon of contrast enhancement intensity, pattern, and kinetics of breast lesions on contrast-enhanced spectral mammography
by: Ayşe Füsun Bekirçavuşoğlu, et al.
Published: (2025-01-01)

Pseudolabel guided pixels contrast for domain adaptive semantic segmentation
by: Jianzi Xiang, et al.
Published: (2024-12-01)

HGNN-GAMS: Heterogeneous Graph Neural Networks for Graph Attribute Mining and Semantic Fusion
by: Yufei Zhao, et al.
Published: (2024-01-01)

The use of ethanol as contrast enhancer in synchrotron X-ray phase-contrast imaging leads to heterogeneous myocardial tissue shrinkage: a case report
by: Gabriel Bernardino, et al.
Published: (2025-01-01)

A Multi-Level Multiple Contrastive Learning Method for Single-Lead Electrocardiogram Atrial Fibrillation Detection
by: Yonggang Zou, et al.
Published: (2025-01-01)

Clinical utility of combined contrast-enhanced ultrasound and intracavitary contrast-enhanced ultrasound in the percutaneous treatment of pyogenic liver abscess
by: Giampiero Francica
Published: (2024-09-01)

Method based on contrastive incremental learning for fine-grained malicious traffic classification
by: Yifeng WANG, et al.
Published: (2023-03-01)

Contrastive meta-learning framework for few-shot cross-lingual text classification
by: GUO Jianming, et al.
Published: (2024-06-01)

Marking Contrastive Topics in a Topic Shift Context: Contrastive Adverbs versus Emphatic Pronouns
by: Jorina Brysbaert, et al.
Published: (2022-12-01)

Comparison of Non-Contrast CT vs. Contrast-Enhanced CT with Both Intravenous and Rectal Contrast Application for Diagnosis of Acute Colonic Diverticulitis: A Multireader, Retrospective Single-Center Study
by: Dorottya Móré, et al.
Published: (2024-12-01)

Hypergraph User Embeddings and Session Contrastive Learning for POI Recommendation
by: Yan Zhang, et al.
Published: (2025-01-01)

Backdoor defense method in federated learning based on contrastive training
by: Jiale ZHANG, et al.
Published: (2024-03-01)

Wafer Defect Classification Algorithm With Label Embedding Using Contrastive Learning
by: Jeongjoon Hwang, et al.
Published: (2025-01-01)

Attentive Self-supervised Contrastive Learning (ASCL) for plant disease classification
by: Getinet Yilma, et al.
Published: (2025-03-01)

FedCLCC: A personalized federated learning algorithm for edge cloud collaboration based on contrastive learning and conditional computing
by: Kangning Yin, et al.
Published: (2025-01-01)

Sequential recommendation based on contrast enhanced time-aware self-attention mechanism
by: YU Yang, et al.
Published: (2025-01-01)

Deep Grassmannian multiview subspace clustering with contrastive learning
by: Rui Wang, et al.
Published: (2024-09-01)

Autism Spectrum Disorder Classification with Interpretability in Children Based on Structural MRI Features Extracted Using Contrastive Variational Autoencoder
by: Ruimin Ma, et al.
Published: (2024-09-01)

Contrast-Induced Acute Kidney Injury in Radiology: Recent Insights and Advances
by: Bassam Alkhalifah
Published: (2024-12-01)

3D LiDAR Multi-Object Tracking Using Multi Positive Contrastive Learning and Deep Reinforcement Learning
by: Minho Cho, et al.
Published: (2025-01-01)

Multifeature Alignment and Matching Network for SAR and Optical Image Registration
by: Xin Hu, et al.
Published: (2025-01-01)

S‐PLM: Structure‐Aware Protein Language Model via Contrastive Learning Between Sequence and Structure
by: Duolin Wang, et al.
Published: (2025-02-01)