Evaluation of relative biological effectiveness of 225Ac and its decay daughters with Monte Carlo track structure simulations

Evaluation of relative biological effectiveness of 225Ac and its decay daughters with Monte Carlo track structure simulations

Abstract Background 225Ac is a radionuclide that can be utilized in targeted alpha therapy (TAT). To accurately assess the absorbed dose and radiation effects in TAT, it is necessary to calculate the relative biological effectiveness (RBE). This study aims to calculate the RBE of 225Ac and its decay...

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Bibliographic Details
Main Authors: Ziyi Hu, Shuiyin Qu, Hongming Liu, Yunhao Zhang, Shuchang Yan, Ankang Hu, Rui Qiu, Zhen Wu, Hui Zhang, Junli Li
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:EJNMMI Physics
Subjects:
Targeted alpha therapy
225Ac
RBE
NASIC
Monte Carlo
Online Access:https://doi.org/10.1186/s40658-025-00765-0
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https://doi.org/10.1186/s40658-025-00765-0

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