A Multicenter Cohort Study on DNA Methylation for Endometrial Cancer Detection in Cervical Scrapings

A Multicenter Cohort Study on DNA Methylation for Endometrial Cancer Detection in Cervical Scrapings

ABSTRACT Background The increasing incidence of endometrial cancer (EC) has highlighted the need for improved early detection methods. This study aimed to develop and validate a novel DNA methylation classifier, EMPap, for EC detection using cervical scrapings. Methods EMPap incorporated the methyla...

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Bibliographic Details
Main Authors: Xiao Ma, Xiaojun Chen, Jing Liang, Jingbo Zhang, Qixi Wu, Dong Wang, Xianghua Huang, Dan Zi, Dexin Chen, Hua Wan, Li Qu, Zhaoyun Jiang, Wenyu Shao, Jie Sun, Luyuan Chang, Yunchao Liu, Qin Zhang, Yanan Li, Yani Ding, Biao Tang, Fang Zhao, Hanqing Zhao, Dongyan Cao
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Cancer Medicine
Subjects:
cervical scrapings
early detection
endometrial cancer
methylation
transvaginal ultrasonography
Online Access:https://doi.org/10.1002/cam4.70361
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