Single-Cell RNA Sequencing, Cell Communication, and Network Pharmacology Reveal the Potential Mechanism of <i>Senecio scandens</i> Buch.-Ham in Hepatocellular Carcinoma Inhibition

Single-Cell RNA Sequencing, Cell Communication, and Network Pharmacology Reveal the Potential Mechanism of <i>Senecio scandens</i> Buch.-Ham in Hepatocellular Carcinoma Inhibition

Background: Hepatocellular carcinoma (HCC), a prevalent form of primary liver malignancy, arises from liver-specific hepatocytes. <i>Senecio scandens</i> Buch.-Ham(Climbing senecio) is a bitter-tasting plant of the Compositae family with anti-tumor properties. This study aims to identify...

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Bibliographic Details
Main Authors: Jiayi Jiang, Haitao Wu, Xikun Jiang, Qing Ou, Zhanpeng Gan, Fangfang Han, Yongming Cai
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
<i>Senecio Scandens</i> Buch.-Ham
hepatocellular carcinoma
network pharmacology
<i>SRC</i>
<i>FOS</i>
Online Access:https://www.mdpi.com/1424-8247/17/12/1707
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