Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 Study

Abstract BackgroundHigh response rates are needed in population-based studies, as nonresponse reduces effective sample size and bias affects accuracy and decreases the generalizability of the study findings. ObjectiveWe tested different strategies to improve respon...

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Main Authors: Christina J Atchison, Nicholas Gilby, Galini Pantelidou, Sam Clemens, Kevin Pickering, Marc Chadeau-Hyam, Deborah Ashby, Wendy S Barclay, Graham S Cooke, Ara Darzi, Steven Riley, Christl A Donnelly, Helen Ward, Paul Elliott
Format: Article
Language:English
Published: JMIR Publications 2025-01-01
Series:JMIR Public Health and Surveillance
Online Access:https://publichealth.jmir.org/2025/1/e60022
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author Christina J Atchison
Nicholas Gilby
Galini Pantelidou
Sam Clemens
Kevin Pickering
Marc Chadeau-Hyam
Deborah Ashby
Wendy S Barclay
Graham S Cooke
Ara Darzi
Steven Riley
Christl A Donnelly
Helen Ward
Paul Elliott
author_facet Christina J Atchison
Nicholas Gilby
Galini Pantelidou
Sam Clemens
Kevin Pickering
Marc Chadeau-Hyam
Deborah Ashby
Wendy S Barclay
Graham S Cooke
Ara Darzi
Steven Riley
Christl A Donnelly
Helen Ward
Paul Elliott
author_sort Christina J Atchison
collection DOAJ
description Abstract BackgroundHigh response rates are needed in population-based studies, as nonresponse reduces effective sample size and bias affects accuracy and decreases the generalizability of the study findings. ObjectiveWe tested different strategies to improve response rate and reduce nonresponse bias in a national population–based COVID-19 surveillance program in England, United Kingdom. MethodsOver 19 rounds, a random sample of individuals aged 5 years and older from the general population in England were invited by mail to complete a web-based questionnaire and return a swab for SARS-CoV-2 testing. We carried out several nested randomized controlled experiments to measure the impact on response rates of different interventions, including (1) variations in invitation and reminder letters and SMS text messages and (2) the offer of a conditional monetary incentive to return a swab, reporting absolute changes in response and relative response rate (95% CIs). ResultsMonetary incentives increased the response rate (completed swabs returned as a proportion of the number of individuals invited) across all age groups, sex at birth, and area deprivation with the biggest increase among the lowest responders, namely teenagers and young adults and those living in more deprived areas. With no monetary incentive, the response rate was 3.4% in participants aged 18‐22 years, increasing to 8.1% with a £10 (US $12.5) incentive, 11.9% with £20 (US $25.0), and 18.2% with £30 (US $37.5) (relative response rate 2.4 [95% CI 2.0-2.9], 3.5 [95% CI 3.0-4.2], and 5.4 [95% CI 4.4-6.7], respectively). Nonmonetary strategies had a modest, if any, impact on response rate. The largest effect was observed for sending an additional swab reminder (SMS text message or email). For example, those receiving an additional SMS text message were more likely to return a completed swab compared to those receiving the standard email-SMS approach, 73.3% versus 70.2%: percentage difference 3.1% (95% CI 2.2%-4.0%). ConclusionsConditional monetary incentives improved response rates to a web-based survey, which required the return of a swab test, particularly for younger age groups. Used in a selective way, incentives may be an effective strategy for improving sample response and representativeness in population-based studies.
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spelling doaj-art-9650b4da159b4f46b39146e3a1be7c2e2025-01-16T15:17:05ZengJMIR PublicationsJMIR Public Health and Surveillance2369-29602025-01-0111e60022e6002210.2196/60022Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 StudyChristina J Atchisonhttp://orcid.org/0000-0001-8304-7389Nicholas Gilbyhttp://orcid.org/0009-0005-0915-8124Galini Pantelidouhttp://orcid.org/0009-0007-3105-5740Sam Clemenshttp://orcid.org/0000-0001-8204-9083Kevin Pickeringhttp://orcid.org/0000-0002-0509-0039Marc Chadeau-Hyamhttp://orcid.org/0000-0001-8341-5436Deborah Ashbyhttp://orcid.org/0000-0003-3146-7466Wendy S Barclayhttp://orcid.org/0000-0002-3948-0895Graham S Cookehttp://orcid.org/0000-0001-6475-5056Ara Darzihttp://orcid.org/0000-0001-7815-7989Steven Rileyhttp://orcid.org/0000-0001-7904-4804Christl A Donnellyhttp://orcid.org/0000-0002-0195-2463Helen Wardhttp://orcid.org/0000-0001-8238-5036Paul Elliotthttp://orcid.org/0000-0002-7511-5684 Abstract BackgroundHigh response rates are needed in population-based studies, as nonresponse reduces effective sample size and bias affects accuracy and decreases the generalizability of the study findings. ObjectiveWe tested different strategies to improve response rate and reduce nonresponse bias in a national population–based COVID-19 surveillance program in England, United Kingdom. MethodsOver 19 rounds, a random sample of individuals aged 5 years and older from the general population in England were invited by mail to complete a web-based questionnaire and return a swab for SARS-CoV-2 testing. We carried out several nested randomized controlled experiments to measure the impact on response rates of different interventions, including (1) variations in invitation and reminder letters and SMS text messages and (2) the offer of a conditional monetary incentive to return a swab, reporting absolute changes in response and relative response rate (95% CIs). ResultsMonetary incentives increased the response rate (completed swabs returned as a proportion of the number of individuals invited) across all age groups, sex at birth, and area deprivation with the biggest increase among the lowest responders, namely teenagers and young adults and those living in more deprived areas. With no monetary incentive, the response rate was 3.4% in participants aged 18‐22 years, increasing to 8.1% with a £10 (US $12.5) incentive, 11.9% with £20 (US $25.0), and 18.2% with £30 (US $37.5) (relative response rate 2.4 [95% CI 2.0-2.9], 3.5 [95% CI 3.0-4.2], and 5.4 [95% CI 4.4-6.7], respectively). Nonmonetary strategies had a modest, if any, impact on response rate. The largest effect was observed for sending an additional swab reminder (SMS text message or email). For example, those receiving an additional SMS text message were more likely to return a completed swab compared to those receiving the standard email-SMS approach, 73.3% versus 70.2%: percentage difference 3.1% (95% CI 2.2%-4.0%). ConclusionsConditional monetary incentives improved response rates to a web-based survey, which required the return of a swab test, particularly for younger age groups. Used in a selective way, incentives may be an effective strategy for improving sample response and representativeness in population-based studies.https://publichealth.jmir.org/2025/1/e60022
spellingShingle Christina J Atchison
Nicholas Gilby
Galini Pantelidou
Sam Clemens
Kevin Pickering
Marc Chadeau-Hyam
Deborah Ashby
Wendy S Barclay
Graham S Cooke
Ara Darzi
Steven Riley
Christl A Donnelly
Helen Ward
Paul Elliott
Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 Study
JMIR Public Health and Surveillance
title Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 Study
title_full Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 Study
title_fullStr Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 Study
title_full_unstemmed Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 Study
title_short Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 Study
title_sort strategies to increase response rate and reduce nonresponse bias in population health research analysis of a series of randomized controlled experiments during a large covid 19 study
url https://publichealth.jmir.org/2025/1/e60022
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