Booster-free anti-retroviral therapy for persons living with HIV and multidrug resistance (B-Free): protocol for a multicentre, multistage, randomised, controlled, non-inferiority trial

Booster-free anti-retroviral therapy for persons living with HIV and multidrug resistance (B-Free): protocol for a multicentre, multistage, randomised, controlled, non-inferiority trial

Introduction Anti-retroviral therapy (ART) simplification strategies are needed for treatment-experienced people with HIV (PWH) and multidrug-resistant viruses. These individuals are commonly treated with boosted ART regimens and are thereby at risk for harmful drug-drug interactions (DDI). In this...

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Main Authors: Nathalie Schwab, Andreas Limacher, Felix Rintelen, Gilles Wandeler, Marc van der Valk, Marie Ballif, Alexandra Calmy, Marcel Stoeckle, Isabelle Peytremann-Bridevaux, Sofia C. Zambrano, Fabrice Bonnet, Matthias Cavassini, Kees Brinkman, Enos Bernasconi, Andri Rauch, Christina Akré, Martina Egloff, Bernard Surial, Dominique Braun, Frédéric Tissot, Patrick Schmid, Christoph A Fux, Tania Mudrikova, Olivier Leleux, Manuela Saúde, Daniela Hirter, Roger Kouyos, David Haerry
Format: Article
Language:English
Published: BMJ Publishing Group 2024-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/11/e094912.full
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