The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms
The G1/S transition is crucial for regulating the initiation of cell division and is highly conserved across eukaryotes. This phase of the cell cycle involves intricate transcriptional controls that are essential for understanding cell proliferation dynamics. The G1/S transition integrates diverse i...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Biotechnology & Biotechnological Equipment |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/13102818.2024.2362842 |
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| author | Cheng Zhou Pan Li Yuwei Qu Jiahe Zuo Zhimin Hao Tongtong Liu |
| author_facet | Cheng Zhou Pan Li Yuwei Qu Jiahe Zuo Zhimin Hao Tongtong Liu |
| author_sort | Cheng Zhou |
| collection | DOAJ |
| description | The G1/S transition is crucial for regulating the initiation of cell division and is highly conserved across eukaryotes. This phase of the cell cycle involves intricate transcriptional controls that are essential for understanding cell proliferation dynamics. The G1/S transition integrates diverse intracellular and extracellular signals, including growth factors and cell sizes. Saccharomyces cerevisiae, an important model organism, plays an integral role in unveiling the regulatory mechanisms of the G1/S transition. Recent studies on the G1/S transition in both yeast and vertebrates have demonstrated a direct correlation between dysregulation of the G1/S transition and the development of cancer. This review explores the G1/S transition regulatory network and its association with cancer formation, providing a theoretical foundation for future research in fundamental cell cycle dynamics and cancer. |
| format | Article |
| id | doaj-art-96313f51dcb04d0980ff49286cae2bdf |
| institution | Kabale University |
| issn | 1310-2818 1314-3530 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Biotechnology & Biotechnological Equipment |
| spelling | doaj-art-96313f51dcb04d0980ff49286cae2bdf2024-12-10T05:42:52ZengTaylor & Francis GroupBiotechnology & Biotechnological Equipment1310-28181314-35302024-12-0138110.1080/13102818.2024.2362842The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanismsCheng Zhou0Pan Li1Yuwei Qu2Jiahe Zuo3Zhimin Hao4Tongtong Liu5Central Laboratory, Affiliated Hospital, Hebei University, Baoding, P.R. ChinaCollege of Plant Protection, Hebei Agricultural University, Baoding, P.R. ChinaCollege of Life Sciences, Hebei Agricultural University, Baoding, P.R. ChinaCollege of Life Sciences, Hebei Agricultural University, Baoding, P.R. ChinaCollege of Life Sciences, Hebei Agricultural University, Baoding, P.R. ChinaAffiliated Hospital, Hebei University, Baoding, P.R. ChinaThe G1/S transition is crucial for regulating the initiation of cell division and is highly conserved across eukaryotes. This phase of the cell cycle involves intricate transcriptional controls that are essential for understanding cell proliferation dynamics. The G1/S transition integrates diverse intracellular and extracellular signals, including growth factors and cell sizes. Saccharomyces cerevisiae, an important model organism, plays an integral role in unveiling the regulatory mechanisms of the G1/S transition. Recent studies on the G1/S transition in both yeast and vertebrates have demonstrated a direct correlation between dysregulation of the G1/S transition and the development of cancer. This review explores the G1/S transition regulatory network and its association with cancer formation, providing a theoretical foundation for future research in fundamental cell cycle dynamics and cancer.https://www.tandfonline.com/doi/10.1080/13102818.2024.2362842Saccharomyces cerevisiaecell cycleG1/S transitioncancer |
| spellingShingle | Cheng Zhou Pan Li Yuwei Qu Jiahe Zuo Zhimin Hao Tongtong Liu The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms Biotechnology & Biotechnological Equipment Saccharomyces cerevisiae cell cycle G1/S transition cancer |
| title | The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms |
| title_full | The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms |
| title_fullStr | The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms |
| title_full_unstemmed | The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms |
| title_short | The regulatory network for the G1/S transition in Saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms |
| title_sort | regulatory network for the g1 s transition in saccharomyces cerevisiae promotes the understanding of cancer developmental mechanisms |
| topic | Saccharomyces cerevisiae cell cycle G1/S transition cancer |
| url | https://www.tandfonline.com/doi/10.1080/13102818.2024.2362842 |
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