Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review
Liposarcoma of the uterine corpus represents an exceptionally rare tumor, with few cases documented in the literature, underscoring its unique histopathologic characteristics and management challenges. This case describes the clinical management of a 57-year-old patient with well-differentiated lipo...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Case Reports in Women's Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214911224000912 |
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| author | Sana Mushtaq Muhammad Arslan Ul Hassan Yan Li Ikran Abdi Aqsa Ahmad HaiNing Li |
| author_facet | Sana Mushtaq Muhammad Arslan Ul Hassan Yan Li Ikran Abdi Aqsa Ahmad HaiNing Li |
| author_sort | Sana Mushtaq |
| collection | DOAJ |
| description | Liposarcoma of the uterine corpus represents an exceptionally rare tumor, with few cases documented in the literature, underscoring its unique histopathologic characteristics and management challenges. This case describes the clinical management of a 57-year-old patient with well-differentiated liposarcoma of the uterine corpus who presented with a three-month history of abdominal pain and distension. She underwent an abdominal hysterectomy followed by chemotherapy but experienced local recurrence in the mesentery and retroperitoneum after 21 months. Tumor resection was performed again, followed by chemotherapy, but the patient experienced a second recurrence 15 months later, involving the small intestine, vaginal stump, and ureter, with evidence of dedifferentiated liposarcoma. A third surgical resection was carried out without administering chemotherapy and the patient remained asymptomatic at follow-up appointments every 3 months for a year. This case highlights the importance of acknowledging the aggressive nature of recurrent liposarcoma, especially its transition into dedifferentiated liposarcoma, and the need for tailored management strategies. |
| format | Article |
| id | doaj-art-9603e56e67584d918f22648c8eb18b22 |
| institution | Kabale University |
| issn | 2214-9112 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Case Reports in Women's Health |
| spelling | doaj-art-9603e56e67584d918f22648c8eb18b222024-12-17T04:59:57ZengElsevierCase Reports in Women's Health2214-91122024-12-0144e00670Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature reviewSana Mushtaq0Muhammad Arslan Ul Hassan1Yan Li2Ikran Abdi3Aqsa Ahmad4HaiNing Li5Department of Gynecology, General Hospital of Ningxia Medical University, Yinchuan 750004, China; The First Clinical Medical College of Ningxia Medical University, Yinchuan 750004, ChinaThe First Clinical Medical College of Ningxia Medical University, Yinchuan 750004, ChinaDepartment of Gynecology, General Hospital of Ningxia Medical University, Yinchuan 750004, China; Corresponding author at: Department of Gynecology, General Hospital of Ningxia Medical University, Yinchuan 750004, China.The First Clinical Medical College of Ningxia Medical University, Yinchuan 750004, ChinaThe First Clinical Medical College of Ningxia Medical University, Yinchuan 750004, ChinaDepartment of Gynecology, General Hospital of Ningxia Medical University, Yinchuan 750004, ChinaLiposarcoma of the uterine corpus represents an exceptionally rare tumor, with few cases documented in the literature, underscoring its unique histopathologic characteristics and management challenges. This case describes the clinical management of a 57-year-old patient with well-differentiated liposarcoma of the uterine corpus who presented with a three-month history of abdominal pain and distension. She underwent an abdominal hysterectomy followed by chemotherapy but experienced local recurrence in the mesentery and retroperitoneum after 21 months. Tumor resection was performed again, followed by chemotherapy, but the patient experienced a second recurrence 15 months later, involving the small intestine, vaginal stump, and ureter, with evidence of dedifferentiated liposarcoma. A third surgical resection was carried out without administering chemotherapy and the patient remained asymptomatic at follow-up appointments every 3 months for a year. This case highlights the importance of acknowledging the aggressive nature of recurrent liposarcoma, especially its transition into dedifferentiated liposarcoma, and the need for tailored management strategies.http://www.sciencedirect.com/science/article/pii/S2214911224000912Well-differentiated liposarcomaDedifferentiationChemotherapyRecurrenceCase report |
| spellingShingle | Sana Mushtaq Muhammad Arslan Ul Hassan Yan Li Ikran Abdi Aqsa Ahmad HaiNing Li Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review Case Reports in Women's Health Well-differentiated liposarcoma Dedifferentiation Chemotherapy Recurrence Case report |
| title | Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review |
| title_full | Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review |
| title_fullStr | Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review |
| title_full_unstemmed | Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review |
| title_short | Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review |
| title_sort | dedifferentiated recurrent liposarcoma of the uterine corpus a case report and literature review |
| topic | Well-differentiated liposarcoma Dedifferentiation Chemotherapy Recurrence Case report |
| url | http://www.sciencedirect.com/science/article/pii/S2214911224000912 |
| work_keys_str_mv | AT sanamushtaq dedifferentiatedrecurrentliposarcomaoftheuterinecorpusacasereportandliteraturereview AT muhammadarslanulhassan dedifferentiatedrecurrentliposarcomaoftheuterinecorpusacasereportandliteraturereview AT yanli dedifferentiatedrecurrentliposarcomaoftheuterinecorpusacasereportandliteraturereview AT ikranabdi dedifferentiatedrecurrentliposarcomaoftheuterinecorpusacasereportandliteraturereview AT aqsaahmad dedifferentiatedrecurrentliposarcomaoftheuterinecorpusacasereportandliteraturereview AT hainingli dedifferentiatedrecurrentliposarcomaoftheuterinecorpusacasereportandliteraturereview |