Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient

Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycyst...

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Main Authors: Chia-Eng Wu, Hsiang-Po Huang, Hong-Nerng Ho, Mei-Jou Chen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124003453
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author Chia-Eng Wu
Hsiang-Po Huang
Hong-Nerng Ho
Mei-Jou Chen
author_facet Chia-Eng Wu
Hsiang-Po Huang
Hong-Nerng Ho
Mei-Jou Chen
author_sort Chia-Eng Wu
collection DOAJ
description Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycystic ovarian morphology on ultrasonography. NTUHi006-A showed stemness, pluripotency and stem cell-like morphology.
format Article
id doaj-art-95e98c57f7ab4ff3bf2e8c005164a031
institution Kabale University
issn 1873-5061
language English
publishDate 2025-02-01
publisher Elsevier
record_format Article
series Stem Cell Research
spelling doaj-art-95e98c57f7ab4ff3bf2e8c005164a0312025-01-13T04:18:43ZengElsevierStem Cell Research1873-50612025-02-0182103647Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patientChia-Eng Wu0Hsiang-Po Huang1Hong-Nerng Ho2Mei-Jou Chen3Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, TaiwanGraduate Institute of Medical Genomics and Proteomics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, TaiwanDepartment of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan; Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, TaiwanDepartment of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan; Livia Shangyu Wan Chair Professor of Obstetrics and Gynecology, National Taiwan University, Taipei, Taiwan Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author.Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycystic ovarian morphology on ultrasonography. NTUHi006-A showed stemness, pluripotency and stem cell-like morphology.http://www.sciencedirect.com/science/article/pii/S1873506124003453
spellingShingle Chia-Eng Wu
Hsiang-Po Huang
Hong-Nerng Ho
Mei-Jou Chen
Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient
Stem Cell Research
title Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient
title_full Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient
title_fullStr Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient
title_full_unstemmed Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient
title_short Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient
title_sort generation of a human induced pluripotent stem cell line ntuhi006 a from a polycystic ovarian syndrome patient
url http://www.sciencedirect.com/science/article/pii/S1873506124003453
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