Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient

Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycyst...

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Bibliographic Details
Main Authors: Chia-Eng Wu, Hsiang-Po Huang, Hong-Nerng Ho, Mei-Jou Chen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124003453
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Summary:Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycystic ovarian morphology on ultrasonography. NTUHi006-A showed stemness, pluripotency and stem cell-like morphology.
ISSN:1873-5061