Distribution of CCR5-Delta32, CCR2-64I, and SDF1-3’A host genetic factors in HIV-infected and uninfected individuals in Luanda, Angola

Distribution of CCR5-Delta32, CCR2-64I, and SDF1-3’A host genetic factors in HIV-infected and uninfected individuals in Luanda, Angola

Abstract Background The HIV/AIDS pandemic remains a public health concern. Studies on host genetic polymorphisms that confer resistance to HIV-1 infection or delay HIV disease progression are scarce in African countries. Herein, we investigate the proportion of the mutated phenotype of the AIDS-rela...

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Main Authors: Cruz S. Sebastião, Victor Pimentel, Domingos Jandondo, Joana M.K. Sebastião, Euclides Sacomboio, Marta Pingarilho, Miguel Brito, Edson Kuatelela Cassinela, Jocelyne Neto de Vasconcelos, Ana B. Abecasis, Joana Morais
Format: Article
Language:English
Published: BMC 2025-05-01
Series:AIDS Research and Therapy
Subjects:
HIV
AIDS-related gene variants
Allelic frequency
Angola
Online Access:https://doi.org/10.1186/s12981-025-00751-7
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