Evaluation of the expression of <i>FLG, AHR</i> and <i>ARNT</i> genes in the skin of patients with atopic dermatitis after phototherapy

Evaluation of the expression of <i>FLG, AHR</i> and <i>ARNT</i> genes in the skin of patients with atopic dermatitis after phototherapy

Background. Ultraviolet irradiation of the skin can activate the cytoplasmic aryl hydrocarbon receptor AhR, which, in combination with its nuclear translocator ARNT binds to the promoter of the FLG gene encoding filaggrin, a protective skin barrier protein. This suggests that the therapeutic effect...

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Main Authors: Irina V. Kozlova, Vadim V. Chikin, Pavel V. Gorodnichev, Kseniya M. Lagun, Nikita Y. Nosov
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2025-03-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
atopic dermatitis
narrow-band ultraviolet phototherapy
aryl hydrocarbon receptor
filaggrin
gene expression
Online Access:https://vestnikdv.ru/jour/article/viewFile/16839/pdf_1
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