Serum detection of blood brain barrier injury in subjects with a history of stroke and transient ischemic attack

Serum detection of blood brain barrier injury in subjects with a history of stroke and transient ischemic attack

Objective: Stroke and transient ischemic attack may have long-term negative effects on the blood-brain barrier (BBB) and promote endothelial inflammation, both of which could increase neurodegeneration and dementia risk beyond the cell death associated with the index event. Methods: Serum from 88 po...

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Main Authors: Scott French, Juan Arias, MD, Ikeoluwapo Bolakale-Rufai, MD, Summan Zahra, MD, Kaneez Zahra Rubab Khakwani, MD, Edward J. Bedrick, PhD, Geidy E. Serrano, PhD, Thomas G. Beach, MD, PhD, Eric Reiman, MD, Craig Weinkauf, MD, PhD
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:JVS - Vascular Science
Subjects:
Blood-based biomarkers
Blood-brain barrier
Endothelial inflammation
Ischemic attack
Stroke
Transient
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350324000178
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