A secondary analysis of cortical atrophy and plasma amyloid β patterns in older patients with cognitive frailty undergoing elective surgery

A secondary analysis of cortical atrophy and plasma amyloid β patterns in older patients with cognitive frailty undergoing elective surgery

Abstract Background The etiology of cognitive impairment in frailty may be related to age or to an independent neurodegenerative process, such as Alzheimer’s disease (AD). In this secondary analysis, we examine cognitive frailty in patients aged 65 and older undergoing elective surgery, and explore...

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Main Authors: Rudolf Mörgeli, Friedrich Borchers, Insa Feinkohl, Sophie K. Piper, Tobias Pischon, Arjen J.C. Slooter, Claudia Spies, Janine Wiebach, Georg Winterer, Norman Zacharias, Florian Lammers-Lietz
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Geriatrics
Subjects:
Frailty
Cognitive frailty
Aging
MRI
Cortical atrophy
Amyloidβ
Online Access:https://doi.org/10.1186/s12877-025-05740-z
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