The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs
The effect of yeast on the treatment and prevention of the cerebrocortical necrosis (CCN) induced experimentally by amprolium in lambs was investigated in this study. Nine healthy lambs (aging between 6 and 8 months, and weighing between 14 and 16 kg) were used as a material. Nine lambs were divided...
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| author | Mahmut Ok Kemal Irmak Mustafa Ortatatlı Veysi Aslan Kemal Çiftçi ismail Şen Fatih M. Birdane |
| author_facet | Mahmut Ok Kemal Irmak Mustafa Ortatatlı Veysi Aslan Kemal Çiftçi ismail Şen Fatih M. Birdane |
| author_sort | Mahmut Ok |
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| description | The effect of yeast on the treatment and prevention of the cerebrocortical necrosis (CCN) induced experimentally by amprolium in lambs was investigated in this study. Nine healthy lambs (aging between 6 and 8 months, and weighing between 14 and 16 kg) were used as a material. Nine lambs were divided into 3 groups. Each group had 3 animals. Amprolium (600 mg/kg/ day) was given to induce CCN orally to all the groups during experiment by stomach tube. Yeast (2 g/kg/day) was given orally to the lambs of group 1 and 3 to treat and to prevent the CCN. The lambs of all the groups exhibited clinical findings related with CCN between 24 and 62 days of the ex-periment, except two lambs of the group 1. Serum ALT and glucose concentrations increased (p <0.05, p<0.01), and plasma thiamine concentration decreased (p <0.05, p<0.01) in all of the lambs. Meningial hyperemia, swelling and oedematous brain were observed in alt of the lambs, excluding lambs 1 and 3 in the necropsy. Histologically, ischemic neuronal changes, perivascular and perineuronal oedema and focal necrosis were determined in cerebellar cortex in all of the lambs, excluding lambs 1 and 3. The results of this study showed that using of yeast might have beneficial in the prevention of the CCN in lambs. |
| format | Article |
| id | doaj-art-94eda5414bbd4e5e9186caa5ab1668f4 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
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| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-94eda5414bbd4e5e9186caa5ab1668f42025-01-03T01:36:52ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531417585488The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambsMahmut Ok0Kemal Irmak1Mustafa Ortatatlı2Veysi Aslan3Kemal Çiftçi4ismail Şen5Fatih M. Birdane6S.Ü. Veteriner Fakültesi İç Hastalıklar Anabilim Dalı, KONYAK.Ü. Veteriner Fakültesi İç Hastalıklar Anabilim Dalı, KARSS.Ü. Veteriner Fakültesi Patoloji Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi İç Hastalıklar Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi Patoloji Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi İç Hastalıklar Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi İç Hastalıklar Anabilim Dalı, KONYAThe effect of yeast on the treatment and prevention of the cerebrocortical necrosis (CCN) induced experimentally by amprolium in lambs was investigated in this study. Nine healthy lambs (aging between 6 and 8 months, and weighing between 14 and 16 kg) were used as a material. Nine lambs were divided into 3 groups. Each group had 3 animals. Amprolium (600 mg/kg/ day) was given to induce CCN orally to all the groups during experiment by stomach tube. Yeast (2 g/kg/day) was given orally to the lambs of group 1 and 3 to treat and to prevent the CCN. The lambs of all the groups exhibited clinical findings related with CCN between 24 and 62 days of the ex-periment, except two lambs of the group 1. Serum ALT and glucose concentrations increased (p <0.05, p<0.01), and plasma thiamine concentration decreased (p <0.05, p<0.01) in all of the lambs. Meningial hyperemia, swelling and oedematous brain were observed in alt of the lambs, excluding lambs 1 and 3 in the necropsy. Histologically, ischemic neuronal changes, perivascular and perineuronal oedema and focal necrosis were determined in cerebellar cortex in all of the lambs, excluding lambs 1 and 3. The results of this study showed that using of yeast might have beneficial in the prevention of the CCN in lambs.http://eurasianjvetsci.org/pdf.php3?id=488lambyeastcerebrocortical necrose |
| spellingShingle | Mahmut Ok Kemal Irmak Mustafa Ortatatlı Veysi Aslan Kemal Çiftçi ismail Şen Fatih M. Birdane The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs Eurasian Journal of Veterinary Sciences lamb yeast cerebrocortical necrose |
| title | The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs |
| title_full | The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs |
| title_fullStr | The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs |
| title_full_unstemmed | The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs |
| title_short | The effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs |
| title_sort | effect of yeast on the treatment and prevention of experimentally induced cerebrocortical necrosis in lambs |
| topic | lamb yeast cerebrocortical necrose |
| url | http://eurasianjvetsci.org/pdf.php3?id=488 |
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