Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in Italy
Urinary tract infections (UTIs) are a common occurrence in cats and dogs. Surveillance of antibiotic resistance trends helps in the prudent selection of suitable antimicrobial agents. However, there are limited available data on this matter in Italy. This retrospective study aimed to investigate the...
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2024-10-01
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| author | Alessandro Bellato Patrizia Robino Maria Cristina Stella Daniela Scalas Paolo Savarino Renato Zanatta Giovanni Re Patrizia Nebbia |
| author_facet | Alessandro Bellato Patrizia Robino Maria Cristina Stella Daniela Scalas Paolo Savarino Renato Zanatta Giovanni Re Patrizia Nebbia |
| author_sort | Alessandro Bellato |
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| description | Urinary tract infections (UTIs) are a common occurrence in cats and dogs. Surveillance of antibiotic resistance trends helps in the prudent selection of suitable antimicrobial agents. However, there are limited available data on this matter in Italy. This retrospective study aimed to investigate the trends of antimicrobial resistance in uropathogenic <i>Escherichia coli</i> (UPEC) isolated from cats and dogs over ten years (January 2014 to October 2023). Three hundred thirty-nine UPEC strains were isolated from urine samples submitted to the Veterinary Teaching Hospital of Torino (Italy). Antimicrobial susceptibility testing was conducted for up to 11 classes of antibacterials, categorized into four categories (A, B, C, and D) following the European Medicine Agency guidelines for prudent antimicrobial use in animals. The results reveal a higher resistance towards compounds in categories C and D, while fewer isolates were resistant to antibacterials in categories B and A. Resistance has steadily increased from 2014 to 2019. Starting from 2020, a decline in resistance is evident in all four categories. The reduction is more pronounced for the categories subject to the greatest restrictions under European and national legislation. The change in resistance trend is in line with findings from other European countries and food-production animals in Italy. |
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| institution | Kabale University |
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| language | English |
| publishDate | 2024-10-01 |
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| spelling | doaj-art-94cc5efc3b7b445a9fa88f4c44c9c91d2024-11-26T18:14:23ZengMDPI AGMicroorganisms2076-26072024-10-011211217510.3390/microorganisms12112175Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in ItalyAlessandro Bellato0Patrizia Robino1Maria Cristina Stella2Daniela Scalas3Paolo Savarino4Renato Zanatta5Giovanni Re6Patrizia Nebbia7Department of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, ItalyBlood Component Production and Validation Center, University Hospital Città della Salute e della Scienza di Torino, 10126 Turin, ItalyDepartment of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, ItalyUrinary tract infections (UTIs) are a common occurrence in cats and dogs. Surveillance of antibiotic resistance trends helps in the prudent selection of suitable antimicrobial agents. However, there are limited available data on this matter in Italy. This retrospective study aimed to investigate the trends of antimicrobial resistance in uropathogenic <i>Escherichia coli</i> (UPEC) isolated from cats and dogs over ten years (January 2014 to October 2023). Three hundred thirty-nine UPEC strains were isolated from urine samples submitted to the Veterinary Teaching Hospital of Torino (Italy). Antimicrobial susceptibility testing was conducted for up to 11 classes of antibacterials, categorized into four categories (A, B, C, and D) following the European Medicine Agency guidelines for prudent antimicrobial use in animals. The results reveal a higher resistance towards compounds in categories C and D, while fewer isolates were resistant to antibacterials in categories B and A. Resistance has steadily increased from 2014 to 2019. Starting from 2020, a decline in resistance is evident in all four categories. The reduction is more pronounced for the categories subject to the greatest restrictions under European and national legislation. The change in resistance trend is in line with findings from other European countries and food-production animals in Italy.https://www.mdpi.com/2076-2607/12/11/2175uropathogenic <i>Escherichia coli</i> (UPEC)antimicrobial resistance (AMR)dogcatsusceptibility testing |
| spellingShingle | Alessandro Bellato Patrizia Robino Maria Cristina Stella Daniela Scalas Paolo Savarino Renato Zanatta Giovanni Re Patrizia Nebbia Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in Italy Microorganisms uropathogenic <i>Escherichia coli</i> (UPEC) antimicrobial resistance (AMR) dog cat susceptibility testing |
| title | Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in Italy |
| title_full | Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in Italy |
| title_fullStr | Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in Italy |
| title_full_unstemmed | Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in Italy |
| title_short | Ten-Year Antimicrobial Resistance Trend in Uropathogenic <i>Escherichia coli</i> (UPEC) Isolated from Dogs and Cats Admitted to a Veterinary Teaching Hospital in Italy |
| title_sort | ten year antimicrobial resistance trend in uropathogenic i escherichia coli i upec isolated from dogs and cats admitted to a veterinary teaching hospital in italy |
| topic | uropathogenic <i>Escherichia coli</i> (UPEC) antimicrobial resistance (AMR) dog cat susceptibility testing |
| url | https://www.mdpi.com/2076-2607/12/11/2175 |
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