A secretome atlas of cardiac fibroblasts from healthy and infarcted mouse hearts

A secretome atlas of cardiac fibroblasts from healthy and infarcted mouse hearts

Abstract Cardiac fibroblasts (CF) are key players after myocardial infarction (MI), but their signaling is only incompletely understood. Here we report a first secretome atlas of CF in control (cCF) and post-MI mouse hearts (miCF), combining a rapid cell isolation technique with SILAC and click chem...

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Main Authors: Jasmin Bahr, Gereon Poschmann, Andreas Jungmann, Martin Busch, Zhaoping Ding, Jens Vogt, Ria Zalfen, Julia Steinhausen, Arlen Aurora Euan Martínez, Thorsten Wachtmeister, Daniel Rickert, Tobias Lautwein, Christina Alter, Junedh M. Amrute, Kory J. Lavine, Karl Köhrer, Bodo Levkau, Patrick Most, Kai Stühler, Julia Hesse, Jürgen Schrader
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08083-y
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