Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series
Renal angiomyolipomas, benign tumors composed of blood vessels, adipose tissue, and smooth muscle, affect approximately 70% to 80% of patients with tuberous sclerosis. Angiomyolipomas smaller than 4 cm are usually asymptomatic, whereas larger ones can cause lumbar pain, anemia, and hematuria. Contra...
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| Language: | English |
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Medrang
2024-12-01
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| Series: | Vascular Specialist International |
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| Online Access: | http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.240039 |
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| author | Ganesh G Gowda Maureen Prativa Tigga Rashmi Hosahalli Sreenath |
| author_facet | Ganesh G Gowda Maureen Prativa Tigga Rashmi Hosahalli Sreenath |
| author_sort | Ganesh G Gowda |
| collection | DOAJ |
| description | Renal angiomyolipomas, benign tumors composed of blood vessels, adipose tissue, and smooth muscle, affect approximately 70% to 80% of patients with tuberous sclerosis. Angiomyolipomas smaller than 4 cm are usually asymptomatic, whereas larger ones can cause lumbar pain, anemia, and hematuria. Contrary to its sporadic counterparts, tuberous sclerosis-associated angiomyolipomas often present at a young age, are multicentric and large, and carry a higher risk of life-threatening hemorrhage. Therapeutic strategies include selective tumor embolization, nephrectomy for severe cases, and medical treatment such as everolimus. Despite a correlation between tuberous sclerosis and renal angiomyolipomas and their described high complication rates in literature, disease awareness in clinical practice remains low. This case series describes the management and outcomes of three patients with tuberous sclerosis-associated renal angiomyolipomas treated with selective arterial embolization. |
| format | Article |
| id | doaj-art-94b95baff8c64f0e981048b29a744e98 |
| institution | Kabale University |
| issn | 2288-7970 2288-7989 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Medrang |
| record_format | Article |
| series | Vascular Specialist International |
| spelling | doaj-art-94b95baff8c64f0e981048b29a744e982024-12-16T02:02:42ZengMedrangVascular Specialist International2288-79702288-79892024-12-014010.5758/vsi.240039vsi.240039Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case SeriesGanesh G Gowda0Maureen Prativa Tigga1Rashmi Hosahalli Sreenath2Department of Vascular Surgery, JSS Academy of Higher Education and Research, Mysuru, IndiaDepartment of Obstetrics and Gynecology, JSS Academy of Higher Education and Research, Mysuru, IndiaDepartment of Obstetrics and Gynecology, JSS Academy of Higher Education and Research, Mysuru, IndiaRenal angiomyolipomas, benign tumors composed of blood vessels, adipose tissue, and smooth muscle, affect approximately 70% to 80% of patients with tuberous sclerosis. Angiomyolipomas smaller than 4 cm are usually asymptomatic, whereas larger ones can cause lumbar pain, anemia, and hematuria. Contrary to its sporadic counterparts, tuberous sclerosis-associated angiomyolipomas often present at a young age, are multicentric and large, and carry a higher risk of life-threatening hemorrhage. Therapeutic strategies include selective tumor embolization, nephrectomy for severe cases, and medical treatment such as everolimus. Despite a correlation between tuberous sclerosis and renal angiomyolipomas and their described high complication rates in literature, disease awareness in clinical practice remains low. This case series describes the management and outcomes of three patients with tuberous sclerosis-associated renal angiomyolipomas treated with selective arterial embolization.http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.240039tuberous sclerosisrenal angiomyolipomaembolization |
| spellingShingle | Ganesh G Gowda Maureen Prativa Tigga Rashmi Hosahalli Sreenath Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series Vascular Specialist International tuberous sclerosis renal angiomyolipoma embolization |
| title | Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series |
| title_full | Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series |
| title_fullStr | Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series |
| title_full_unstemmed | Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series |
| title_short | Management of Renal Angiomyolipomas in Tuberous Sclerosis: A Case Series |
| title_sort | management of renal angiomyolipomas in tuberous sclerosis a case series |
| topic | tuberous sclerosis renal angiomyolipoma embolization |
| url | http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.240039 |
| work_keys_str_mv | AT ganeshggowda managementofrenalangiomyolipomasintuberoussclerosisacaseseries AT maureenprativatigga managementofrenalangiomyolipomasintuberoussclerosisacaseseries AT rashmihosahallisreenath managementofrenalangiomyolipomasintuberoussclerosisacaseseries |