Multitracer Positron Emission Tomographic Imaging of Exogenous Gene Expression Mediated by a Universal Herpes Simplex Virus 1 Amplicon Vector

Multitracer Positron Emission Tomographic Imaging of Exogenous Gene Expression Mediated by a Universal Herpes Simplex Virus 1 Amplicon Vector

To develop efficient and safe gene therapy approaches, the herpes simplex virus type 1 thymidine kinase gene (HSV-1- tk ) has been shown to function as a marker gene for the direct noninvasive in vivo localization of thymidine kinase (TK) expression by positron emission tomography (PET) using radiol...

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Bibliographic Details
Main Authors: Christiane Kummer, Alexandra Winkeler, Claus Dittmar, Bernd Bauer, Maria Adele Rueger, Benedikt Rueckriem, Michael T. Heneka, Stefan Vollmar, Klaus Wienhard, Cornel Fraefel, Wolf-Dieter Heiss, Andreas H. Jacobs
Format: Article
Language:English
Published: SAGE Publishing 2007-05-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2007.00015
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