Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study

Background: People are very concerned about the adverse effects of Omicron infection on delivery modes, duration of labor, and the postpartum status of pregnant women and neonates. Methods: 382 pregnant women (Omicron group: 136 cases; non-Omicron group: 246 cases) giving birth in our hospital were...

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Main Authors: Jing Wang, Lingfei Ge, Kai Zhou, Yi Jiang, Mengqi Pang, Jiaqi Wang, Yuxian Zhu, Lingli Zhu, Xiaoxiao Jin, Zeying Chai, Tao Hsin Tung, Hongping Lu, Bo Shen, Lingzhi Zheng
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Language:English
Published: Elsevier 2024-11-01
Series:Travel Medicine and Infectious Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S1477893924000760
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author Jing Wang
Lingfei Ge
Kai Zhou
Yi Jiang
Mengqi Pang
Jiaqi Wang
Yuxian Zhu
Lingli Zhu
Xiaoxiao Jin
Zeying Chai
Tao Hsin Tung
Hongping Lu
Bo Shen
Lingzhi Zheng
author_facet Jing Wang
Lingfei Ge
Kai Zhou
Yi Jiang
Mengqi Pang
Jiaqi Wang
Yuxian Zhu
Lingli Zhu
Xiaoxiao Jin
Zeying Chai
Tao Hsin Tung
Hongping Lu
Bo Shen
Lingzhi Zheng
author_sort Jing Wang
collection DOAJ
description Background: People are very concerned about the adverse effects of Omicron infection on delivery modes, duration of labor, and the postpartum status of pregnant women and neonates. Methods: 382 pregnant women (Omicron group: 136 cases; non-Omicron group: 246 cases) giving birth in our hospital were collected, demographic characteristics, vaccination, clinical manifestation and medication, delivery outcomes of pregnant women and neonates were recorded. Delivery outcomes were compared between the Omicron and non-Omicron groups, acute infection and non-acute infection groups to explore the relationship between adverse delivery outcomes and Omicron infection. Results: Pregnant women in the Omicron group had a longer hospitalization time (6.3 ± 3.6 days vs.5.5 ± 2.3 days), more 2-hour postpartum hemorrhage (291.7 ± 104.9 mL vs.262.7 ± 91.2 mL) and higher neonatal-pediatric transfer rate (20.6 % vs. 2.8 %), which might be associated with fetal distress, prenatal fever and pneumonia/respiratory distress. Neonates transferred to pediatrics due to jaundice were unique in the Omicron group. Fever-pregnant women have a more prolonged second stage of labor and hospital stay while coughing or expectoration ones have a shorter third stage of labor. Delivery outcomes did not differ whether the infected pregnant women were in the acute phase and whether to use antipyretics. Conclusion: Omicron infection can increase the 2-hour postpartum hemorrhage volume and the neonatal-pediatric transfer rate. The symptoms can affect the duration of labor and hospital stay. However, whether the infected pregnant women are in the acute phase or use antipyretics do not affect the delivery outcome.
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spelling doaj-art-947399b58ec7416d81d8ec6af9e448c12024-11-27T05:01:52ZengElsevierTravel Medicine and Infectious Disease1873-04422024-11-0162102759Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort studyJing Wang0Lingfei Ge1Kai Zhou2Yi Jiang3Mengqi Pang4Jiaqi Wang5Yuxian Zhu6Lingli Zhu7Xiaoxiao Jin8Zeying Chai9Tao Hsin Tung10Hongping Lu11Bo Shen12Lingzhi Zheng13Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaEvidence-Based Medicine Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, ChinaDepartment of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, China; Corresponding author.Department of Obstetrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Road, Linhai, Taizhou, Zhejiang Province, China; Corresponding author.Background: People are very concerned about the adverse effects of Omicron infection on delivery modes, duration of labor, and the postpartum status of pregnant women and neonates. Methods: 382 pregnant women (Omicron group: 136 cases; non-Omicron group: 246 cases) giving birth in our hospital were collected, demographic characteristics, vaccination, clinical manifestation and medication, delivery outcomes of pregnant women and neonates were recorded. Delivery outcomes were compared between the Omicron and non-Omicron groups, acute infection and non-acute infection groups to explore the relationship between adverse delivery outcomes and Omicron infection. Results: Pregnant women in the Omicron group had a longer hospitalization time (6.3 ± 3.6 days vs.5.5 ± 2.3 days), more 2-hour postpartum hemorrhage (291.7 ± 104.9 mL vs.262.7 ± 91.2 mL) and higher neonatal-pediatric transfer rate (20.6 % vs. 2.8 %), which might be associated with fetal distress, prenatal fever and pneumonia/respiratory distress. Neonates transferred to pediatrics due to jaundice were unique in the Omicron group. Fever-pregnant women have a more prolonged second stage of labor and hospital stay while coughing or expectoration ones have a shorter third stage of labor. Delivery outcomes did not differ whether the infected pregnant women were in the acute phase and whether to use antipyretics. Conclusion: Omicron infection can increase the 2-hour postpartum hemorrhage volume and the neonatal-pediatric transfer rate. The symptoms can affect the duration of labor and hospital stay. However, whether the infected pregnant women are in the acute phase or use antipyretics do not affect the delivery outcome.http://www.sciencedirect.com/science/article/pii/S1477893924000760Delivery outcomesOmicronPregnant womenSymptomsMedication
spellingShingle Jing Wang
Lingfei Ge
Kai Zhou
Yi Jiang
Mengqi Pang
Jiaqi Wang
Yuxian Zhu
Lingli Zhu
Xiaoxiao Jin
Zeying Chai
Tao Hsin Tung
Hongping Lu
Bo Shen
Lingzhi Zheng
Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study
Travel Medicine and Infectious Disease
Delivery outcomes
Omicron
Pregnant women
Symptoms
Medication
title Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study
title_full Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study
title_fullStr Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study
title_full_unstemmed Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study
title_short Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study
title_sort effect of omicron infection on maternal and neonatal delivery outcomes a retrospective cohort study
topic Delivery outcomes
Omicron
Pregnant women
Symptoms
Medication
url http://www.sciencedirect.com/science/article/pii/S1477893924000760
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