Impact of blood centrifugation on the parameters of thrombin generation assay revisited to look for possible revision of the current guidance

Impact of blood centrifugation on the parameters of thrombin generation assay revisited to look for possible revision of the current guidance

Blood centrifugation affects thrombin generation assays (TGA). Current guidance recommends double-centrifugation, which is uncommon in clinical laboratories.We evaluated the impact of 4 centrifugation speeds on TGA performed with low-triggers (1pM tissue-factor/1.0 μM phospholipids) or high-triggers...

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Bibliographic Details
Main Authors: Erica Scalambrino, Marigrazia Clerici, Flora Peyvandi, Armando Tripodi
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Practical Laboratory Medicine
Subjects:
Lag-time
Peak-thrombin
ETP
Standardization
Blood centrifugation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551725000319
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