Hepatic Angiomyolipoma: A Case Report and Literature Review

Hepatic angiomyolipoma (HAML) is an uncommon primary liver tumor with limited reported cases in the literature. It is composed of varying amounts of fat, smooth muscle, and blood vessels, typically non-malignant proliferation. It usually presents diagnostic challenges due to diverse imaging characte...

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Main Authors: Ramzi Tababi MD, Mouna Medhioub MD, Ines Soussi MD, Imen Noomen MD, Yassine Kallel MD, Manel Yakoubi MD, Asma Ben Mohamed MD, Moufida Mahmoudi MD, Ghada Gharbi MD, Mahdi Bouassida MD, Emna Chelbi MD, Khaled Bouzaidi MD, Amal Khsiba MD, Mohamed Lamine Hamzaoui MD
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/23247096241306542
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author Ramzi Tababi MD
Mouna Medhioub MD
Ines Soussi MD
Imen Noomen MD
Yassine Kallel MD
Manel Yakoubi MD
Asma Ben Mohamed MD
Moufida Mahmoudi MD
Ghada Gharbi MD
Mahdi Bouassida MD
Emna Chelbi MD
Khaled Bouzaidi MD
Amal Khsiba MD
Mohamed Lamine Hamzaoui MD
author_facet Ramzi Tababi MD
Mouna Medhioub MD
Ines Soussi MD
Imen Noomen MD
Yassine Kallel MD
Manel Yakoubi MD
Asma Ben Mohamed MD
Moufida Mahmoudi MD
Ghada Gharbi MD
Mahdi Bouassida MD
Emna Chelbi MD
Khaled Bouzaidi MD
Amal Khsiba MD
Mohamed Lamine Hamzaoui MD
author_sort Ramzi Tababi MD
collection DOAJ
description Hepatic angiomyolipoma (HAML) is an uncommon primary liver tumor with limited reported cases in the literature. It is composed of varying amounts of fat, smooth muscle, and blood vessels, typically non-malignant proliferation. It usually presents diagnostic challenges due to diverse imaging characteristics. We present a case of a 50-year-old female with a small HAML causing mild abdominal pain. It displayed radiographic characteristics mimicking hepatocellular carcinoma (HCC), and subsequent diagnosis was established upon histopathological findings of liver biopsy. The patient was radiologically monitored, and then she underwent surgical resection later on because of the size increase. Follow-up showed no signs of recurrence at 3 months. This case highlights the importance of histologic diagnosis of HAML if there are suggestive imaging features, given the variety of differential diagnoses. Symptoms or tumor growth is to be considered as warning signs that should lead to surgical resection, which remains the primary treatment modality.
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publisher SAGE Publishing
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series Journal of Investigative Medicine High Impact Case Reports
spelling doaj-art-94325b7745b442408f7e7c9fb0a356db2024-12-13T01:03:28ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962024-12-011210.1177/23247096241306542Hepatic Angiomyolipoma: A Case Report and Literature ReviewRamzi Tababi MD0Mouna Medhioub MD1Ines Soussi MD2Imen Noomen MD3Yassine Kallel MD4Manel Yakoubi MD5Asma Ben Mohamed MD6Moufida Mahmoudi MD7Ghada Gharbi MD8Mahdi Bouassida MD9Emna Chelbi MD10Khaled Bouzaidi MD11Amal Khsiba MD12Mohamed Lamine Hamzaoui MD13Gastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaRadiology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaPathology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGeneral Surgery Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGeneral Surgery Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaPathology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaRadiology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaGastroenterology Department, Mohamed Taher Maamouri University Hospital, Nabeul, TunisiaHepatic angiomyolipoma (HAML) is an uncommon primary liver tumor with limited reported cases in the literature. It is composed of varying amounts of fat, smooth muscle, and blood vessels, typically non-malignant proliferation. It usually presents diagnostic challenges due to diverse imaging characteristics. We present a case of a 50-year-old female with a small HAML causing mild abdominal pain. It displayed radiographic characteristics mimicking hepatocellular carcinoma (HCC), and subsequent diagnosis was established upon histopathological findings of liver biopsy. The patient was radiologically monitored, and then she underwent surgical resection later on because of the size increase. Follow-up showed no signs of recurrence at 3 months. This case highlights the importance of histologic diagnosis of HAML if there are suggestive imaging features, given the variety of differential diagnoses. Symptoms or tumor growth is to be considered as warning signs that should lead to surgical resection, which remains the primary treatment modality.https://doi.org/10.1177/23247096241306542
spellingShingle Ramzi Tababi MD
Mouna Medhioub MD
Ines Soussi MD
Imen Noomen MD
Yassine Kallel MD
Manel Yakoubi MD
Asma Ben Mohamed MD
Moufida Mahmoudi MD
Ghada Gharbi MD
Mahdi Bouassida MD
Emna Chelbi MD
Khaled Bouzaidi MD
Amal Khsiba MD
Mohamed Lamine Hamzaoui MD
Hepatic Angiomyolipoma: A Case Report and Literature Review
Journal of Investigative Medicine High Impact Case Reports
title Hepatic Angiomyolipoma: A Case Report and Literature Review
title_full Hepatic Angiomyolipoma: A Case Report and Literature Review
title_fullStr Hepatic Angiomyolipoma: A Case Report and Literature Review
title_full_unstemmed Hepatic Angiomyolipoma: A Case Report and Literature Review
title_short Hepatic Angiomyolipoma: A Case Report and Literature Review
title_sort hepatic angiomyolipoma a case report and literature review
url https://doi.org/10.1177/23247096241306542
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