The determination of the selenium levels in the blood and tissues of mice given selenium

In this study, the selenium levels in the blood and tissue samples of mice experimentally poisoned with selenium were investigated. In the investigation, 210 mice were used. The blood and tissue samples were taken at 5, 10, 15, 30th min, 1, 2, 4, 8, 24, 48 and 72th hours following the intraperitonea...

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Main Authors: İbrahim Pirinçci, Ahmet Ateşşahin, İzzet Karahan, İrfan Demirbaş
Format: Article
Language:English
Published: Selcuk University Press
Series:Eurasian Journal of Veterinary Sciences
Subjects:
Online Access:http://eurasianjvetsci.org/pdf.php3?id=363
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author İbrahim Pirinçci
Ahmet Ateşşahin
İzzet Karahan
İrfan Demirbaş
author_facet İbrahim Pirinçci
Ahmet Ateşşahin
İzzet Karahan
İrfan Demirbaş
author_sort İbrahim Pirinçci
collection DOAJ
description In this study, the selenium levels in the blood and tissue samples of mice experimentally poisoned with selenium were investigated. In the investigation, 210 mice were used. The blood and tissue samples were taken at 5, 10, 15, 30th min, 1, 2, 4, 8, 24, 48 and 72th hours following the intraperitoneal administration of selenium at the doses of 1 and 2 mg/kg. Similarly, the blood and tissue samples were taken at 30. 60 and 90th days following the oral administration ol selenium at doses of 0.5, 3 and 10 ppm. The selenium levels in the samples were spect-rophotometrically measured at 420 nm. In conclusion, the selenium levels were determined to increase depending on time and dose in mice treated with selenium orally. Whereas, when it was intraperitoneal^ given, the selenium levels were defined to reach to the maximum levels in blood at 10 and 30th min; in liver at 30th min and 2 nd hours; in kidney at 1st hour; in spleen at 15 and 30th min; in heart at 10 and 15th min; in muscle at 24 and 8th hours according to doses, respectively. Afterwards, the selenium levels were established to decrease, gradually.
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language English
publisher Selcuk University Press
record_format Article
series Eurasian Journal of Veterinary Sciences
spelling doaj-art-93d8dd89333f41fea14c36b939b096a92025-01-02T22:35:04ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531622732363The determination of the selenium levels in the blood and tissues of mice given seleniumİbrahim PirinçciAhmet Ateşşahinİzzet Karahanİrfan DemirbaşIn this study, the selenium levels in the blood and tissue samples of mice experimentally poisoned with selenium were investigated. In the investigation, 210 mice were used. The blood and tissue samples were taken at 5, 10, 15, 30th min, 1, 2, 4, 8, 24, 48 and 72th hours following the intraperitoneal administration of selenium at the doses of 1 and 2 mg/kg. Similarly, the blood and tissue samples were taken at 30. 60 and 90th days following the oral administration ol selenium at doses of 0.5, 3 and 10 ppm. The selenium levels in the samples were spect-rophotometrically measured at 420 nm. In conclusion, the selenium levels were determined to increase depending on time and dose in mice treated with selenium orally. Whereas, when it was intraperitoneal^ given, the selenium levels were defined to reach to the maximum levels in blood at 10 and 30th min; in liver at 30th min and 2 nd hours; in kidney at 1st hour; in spleen at 15 and 30th min; in heart at 10 and 15th min; in muscle at 24 and 8th hours according to doses, respectively. Afterwards, the selenium levels were established to decrease, gradually.http://eurasianjvetsci.org/pdf.php3?id=363selenium levelsbloodtissuesmice
spellingShingle İbrahim Pirinçci
Ahmet Ateşşahin
İzzet Karahan
İrfan Demirbaş
The determination of the selenium levels in the blood and tissues of mice given selenium
Eurasian Journal of Veterinary Sciences
selenium levels
blood
tissues
mice
title The determination of the selenium levels in the blood and tissues of mice given selenium
title_full The determination of the selenium levels in the blood and tissues of mice given selenium
title_fullStr The determination of the selenium levels in the blood and tissues of mice given selenium
title_full_unstemmed The determination of the selenium levels in the blood and tissues of mice given selenium
title_short The determination of the selenium levels in the blood and tissues of mice given selenium
title_sort determination of the selenium levels in the blood and tissues of mice given selenium
topic selenium levels
blood
tissues
mice
url http://eurasianjvetsci.org/pdf.php3?id=363
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