Case report and literature review of complex renal angiomyolipoma
Abstract Renal angiomyolipoma (AML) is a rare benign renal tumor with notable clinical implications, including potential compression of adjacent organs and a heightened risk of spontaneous hemorrhage, particularly when the tumor grows large. We present a complex case involving renal AML in a 52-year...
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| Language: | English |
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BMC
2025-07-01
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| Series: | BMC Urology |
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| Online Access: | https://doi.org/10.1186/s12894-025-01849-w |
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| author | Junwei Li Jiwang Deng Zijian Tang Chen Wang Junjin Zhang Bin Lai Yongmao Zeng Lian Peng Qingjiang Chen Shuangquan Gao Liqun Zhong Yuefu Han |
| author_facet | Junwei Li Jiwang Deng Zijian Tang Chen Wang Junjin Zhang Bin Lai Yongmao Zeng Lian Peng Qingjiang Chen Shuangquan Gao Liqun Zhong Yuefu Han |
| author_sort | Junwei Li |
| collection | DOAJ |
| description | Abstract Renal angiomyolipoma (AML) is a rare benign renal tumor with notable clinical implications, including potential compression of adjacent organs and a heightened risk of spontaneous hemorrhage, particularly when the tumor grows large. We present a complex case involving renal AML in a 52-year-old male patient who exhibited persistent left flank pain. Radiological imaging revealed a bilateral AML, with the most significant lesion on the left measuring approximately 13.5 × 19.3 × 15.6 cm. This lesion was associated with multiple renal stones, fluid accumulation, and atrophy of the left kidney. Surgical intervention was necessary, leading to open nephrectomy and removal of the left renal mass. Histopathological examination confirmed the diagnosis of renal angiomyolipoma and left renal atrophy. This case report provides critical insights into the multifaceted nature of renal AML, covering its pathogenesis, clinical presentation, diagnosis, and treatment, and thus enhances the understanding and management of this condition in clinical practice. |
| format | Article |
| id | doaj-art-93cb5beb881e40b69b01a7ef7ddde978 |
| institution | Kabale University |
| issn | 1471-2490 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj-art-93cb5beb881e40b69b01a7ef7ddde9782025-08-20T04:01:35ZengBMCBMC Urology1471-24902025-07-012511610.1186/s12894-025-01849-wCase report and literature review of complex renal angiomyolipomaJunwei Li0Jiwang Deng1Zijian Tang2Chen Wang3Junjin Zhang4Bin Lai5Yongmao Zeng6Lian Peng7Qingjiang Chen8Shuangquan Gao9Liqun Zhong10Yuefu Han11Guangdong Medical UniversityYuebei People’s Hospital Joint Postgraduate Training Base, Guangdong Medical UniversityDepartment of Urology, Yuebei People’s Hospital Affiliated to Shantou University Medical CollegeDepartment of Urology, Yuebei People’s Hospital Affiliated to Shantou University Medical CollegeGuangdong Medical UniversityYuebei People’s Hospital Joint Postgraduate Training Base, Guangdong Medical UniversityYuebei People’s Hospital Joint Postgraduate Training Base, Guangdong Medical UniversityYuebei People’s Hospital Joint Postgraduate Training Base, Guangdong Medical UniversityYuebei People’s Hospital Joint Postgraduate Training Base, Guangdong Medical UniversityDepartment of Pathology, Yuebei People’s Hospital Affiliated to Shantou University Medical CollegeDepartment of Urology, Yuebei People’s Hospital Affiliated to Shantou University Medical CollegeYuebei People’s Hospital Joint Postgraduate Training Base, Guangdong Medical UniversityAbstract Renal angiomyolipoma (AML) is a rare benign renal tumor with notable clinical implications, including potential compression of adjacent organs and a heightened risk of spontaneous hemorrhage, particularly when the tumor grows large. We present a complex case involving renal AML in a 52-year-old male patient who exhibited persistent left flank pain. Radiological imaging revealed a bilateral AML, with the most significant lesion on the left measuring approximately 13.5 × 19.3 × 15.6 cm. This lesion was associated with multiple renal stones, fluid accumulation, and atrophy of the left kidney. Surgical intervention was necessary, leading to open nephrectomy and removal of the left renal mass. Histopathological examination confirmed the diagnosis of renal angiomyolipoma and left renal atrophy. This case report provides critical insights into the multifaceted nature of renal AML, covering its pathogenesis, clinical presentation, diagnosis, and treatment, and thus enhances the understanding and management of this condition in clinical practice.https://doi.org/10.1186/s12894-025-01849-wRenal angiomyolipomaImmunohistochemistryDiagnosis |
| spellingShingle | Junwei Li Jiwang Deng Zijian Tang Chen Wang Junjin Zhang Bin Lai Yongmao Zeng Lian Peng Qingjiang Chen Shuangquan Gao Liqun Zhong Yuefu Han Case report and literature review of complex renal angiomyolipoma BMC Urology Renal angiomyolipoma Immunohistochemistry Diagnosis |
| title | Case report and literature review of complex renal angiomyolipoma |
| title_full | Case report and literature review of complex renal angiomyolipoma |
| title_fullStr | Case report and literature review of complex renal angiomyolipoma |
| title_full_unstemmed | Case report and literature review of complex renal angiomyolipoma |
| title_short | Case report and literature review of complex renal angiomyolipoma |
| title_sort | case report and literature review of complex renal angiomyolipoma |
| topic | Renal angiomyolipoma Immunohistochemistry Diagnosis |
| url | https://doi.org/10.1186/s12894-025-01849-w |
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