Impact of digital health interventions on glycemic control and weight management

Abstract This retrospective cohort study evaluates the impact of an AI-supported continuous glucose monitoring (CGM) mobile app (“January V2”) on glycemic control and weight management in 944 users, including healthy individuals and those with prediabetes or type 2 diabetes (T2D). The app, leveragin...

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Main Authors: Arvind Veluvali, Ashkan Dehghani Zahedani, Amir Hosseinian, Nima Aghaeepour, Tracey McLaughlin, Mark Woodward, Alex DiTullio, Noosheen Hashemi, Michael P. Snyder
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01430-7
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author Arvind Veluvali
Ashkan Dehghani Zahedani
Amir Hosseinian
Nima Aghaeepour
Tracey McLaughlin
Mark Woodward
Alex DiTullio
Noosheen Hashemi
Michael P. Snyder
author_facet Arvind Veluvali
Ashkan Dehghani Zahedani
Amir Hosseinian
Nima Aghaeepour
Tracey McLaughlin
Mark Woodward
Alex DiTullio
Noosheen Hashemi
Michael P. Snyder
author_sort Arvind Veluvali
collection DOAJ
description Abstract This retrospective cohort study evaluates the impact of an AI-supported continuous glucose monitoring (CGM) mobile app (“January V2”) on glycemic control and weight management in 944 users, including healthy individuals and those with prediabetes or type 2 diabetes (T2D). The app, leveraging AI to personalize feedback, tracked users’ food intake, activity, and glucose responses over 14 days. Significant improvements in time in range (TIR) were observed, particularly in users with lower baseline TIR. Healthy users’ TIR increased from 74.7% to 85.5% (p < 0.0001), while T2D users’ TIR improved from 49.7% to 57.4% (p < 0.0004). Higher app engagement correlated with greater TIR improvements. Users also experienced an average weight reduction of 3.3 lbs over 33 days. These findings suggest that AI-enhanced digital health interventions can improve glycemic control and promote weight loss, particularly when users are actively engaged.
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publisher Nature Portfolio
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series npj Digital Medicine
spelling doaj-art-93bf199fd17d4346a94ae5b4b360d1812025-01-12T12:41:01ZengNature Portfolionpj Digital Medicine2398-63522025-01-018111110.1038/s41746-025-01430-7Impact of digital health interventions on glycemic control and weight managementArvind Veluvali0Ashkan Dehghani Zahedani1Amir Hosseinian2Nima Aghaeepour3Tracey McLaughlin4Mark Woodward5Alex DiTullio6Noosheen Hashemi7Michael P. Snyder8January AIJanuary AIJanuary AIJanuary AIJanuary AIJanuary AIJanuary AIJanuary AIJanuary AIAbstract This retrospective cohort study evaluates the impact of an AI-supported continuous glucose monitoring (CGM) mobile app (“January V2”) on glycemic control and weight management in 944 users, including healthy individuals and those with prediabetes or type 2 diabetes (T2D). The app, leveraging AI to personalize feedback, tracked users’ food intake, activity, and glucose responses over 14 days. Significant improvements in time in range (TIR) were observed, particularly in users with lower baseline TIR. Healthy users’ TIR increased from 74.7% to 85.5% (p < 0.0001), while T2D users’ TIR improved from 49.7% to 57.4% (p < 0.0004). Higher app engagement correlated with greater TIR improvements. Users also experienced an average weight reduction of 3.3 lbs over 33 days. These findings suggest that AI-enhanced digital health interventions can improve glycemic control and promote weight loss, particularly when users are actively engaged.https://doi.org/10.1038/s41746-025-01430-7
spellingShingle Arvind Veluvali
Ashkan Dehghani Zahedani
Amir Hosseinian
Nima Aghaeepour
Tracey McLaughlin
Mark Woodward
Alex DiTullio
Noosheen Hashemi
Michael P. Snyder
Impact of digital health interventions on glycemic control and weight management
npj Digital Medicine
title Impact of digital health interventions on glycemic control and weight management
title_full Impact of digital health interventions on glycemic control and weight management
title_fullStr Impact of digital health interventions on glycemic control and weight management
title_full_unstemmed Impact of digital health interventions on glycemic control and weight management
title_short Impact of digital health interventions on glycemic control and weight management
title_sort impact of digital health interventions on glycemic control and weight management
url https://doi.org/10.1038/s41746-025-01430-7
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