Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study
BackgroundSarcopenia, sarcopenic obesity, and hypertension are all widespread public health problems in middle-aged and older populations, and their association is controversial. The purpose of this study is to analyze the relationship between obesity, sarcopenia, and sarcopenic obesity with hyperte...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1479169/full |
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| author | Runfen Du Junchao Yuan Yunda Huang Guihua Jiang Zhiping Duan Hong Yang Wei Huang |
| author_facet | Runfen Du Junchao Yuan Yunda Huang Guihua Jiang Zhiping Duan Hong Yang Wei Huang |
| author_sort | Runfen Du |
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| description | BackgroundSarcopenia, sarcopenic obesity, and hypertension are all widespread public health problems in middle-aged and older populations, and their association is controversial. The purpose of this study is to analyze the relationship between obesity, sarcopenia, and sarcopenic obesity with hypertension in a middle-aged and older community population in China through a large-scale longitudinal design.MethodsIn this cohort study with 7 years of follow-up, the study population was drawn from participants in the China Health and Retirement Longitudinal Study (CHARLS) in 2011 and followed up in 2013, 2015, and 2018. The diagnostic criteria for sarcopenia were based on the consensus recommendations issued by the Asian Working Group for Sarcopenia (AWGS) in 2019. The diagnosis of obesity is based on body mass index and waist circumference. Sarcopenic obesity is defined as the coexistence of sarcopenia and obesity. Cox proportional risk regression models were used to analyze the association of obesity, sarcopenia, and sarcopenic obesity with hypertension.ResultsA total of 7,301 participants with a mean age of 58 ± 8.8 were enrolled in the study, and 51.9% females. A total of 1,957 participants had a new onset of hypertension after 7 years of follow-up. In a multifactorial analysis, obesity and sarcopenic obesity were associated with hypertension; hazard ratios (HRs) and 95% confidence intervals (CIs) were 1.67 (1.43 ~ 1.96), p < 0.001, and 1.61 (1.09 ~ 2.37), p = 0.017. Sarcopenia and hypertension were not significantly associated; the HR and 95% CI were 1.17 (0.9 ~ 1.52), p = 0.23.ConclusionThere is no significant correlation between sarcopenia and hypertension, but obesity and sarcopenic obesity increase the risk of hypertension. Targeted management of middle-aged and older people with sarcopenic obesity is needed in public health efforts. |
| format | Article |
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| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj-art-9391d41f4bdc482e8efb26d8eb040ed12025-01-15T05:11:09ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011210.3389/fpubh.2024.14791691479169Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort studyRunfen Du0Junchao Yuan1Yunda Huang2Guihua Jiang3Zhiping Duan4Hong Yang5Wei Huang6Department of Geriatrics, The Third People’s Hospital of Yunnan Province, Kunming, Yunnan, ChinaDepartment of Endocrinology, The First People’s Hospital of Yunnan Province, Kunming, Yunnan, ChinaDepartment of Geriatrics, The Third People’s Hospital of Yunnan Province, Kunming, Yunnan, ChinaDepartment of Geriatrics, The Third People’s Hospital of Yunnan Province, Kunming, Yunnan, ChinaDepartment of Geriatrics, The Third People’s Hospital of Yunnan Province, Kunming, Yunnan, ChinaDepartment of Geriatrics, The Third People’s Hospital of Yunnan Province, Kunming, Yunnan, ChinaDepartment of Geriatrics, The Third People’s Hospital of Yunnan Province, Kunming, Yunnan, ChinaBackgroundSarcopenia, sarcopenic obesity, and hypertension are all widespread public health problems in middle-aged and older populations, and their association is controversial. The purpose of this study is to analyze the relationship between obesity, sarcopenia, and sarcopenic obesity with hypertension in a middle-aged and older community population in China through a large-scale longitudinal design.MethodsIn this cohort study with 7 years of follow-up, the study population was drawn from participants in the China Health and Retirement Longitudinal Study (CHARLS) in 2011 and followed up in 2013, 2015, and 2018. The diagnostic criteria for sarcopenia were based on the consensus recommendations issued by the Asian Working Group for Sarcopenia (AWGS) in 2019. The diagnosis of obesity is based on body mass index and waist circumference. Sarcopenic obesity is defined as the coexistence of sarcopenia and obesity. Cox proportional risk regression models were used to analyze the association of obesity, sarcopenia, and sarcopenic obesity with hypertension.ResultsA total of 7,301 participants with a mean age of 58 ± 8.8 were enrolled in the study, and 51.9% females. A total of 1,957 participants had a new onset of hypertension after 7 years of follow-up. In a multifactorial analysis, obesity and sarcopenic obesity were associated with hypertension; hazard ratios (HRs) and 95% confidence intervals (CIs) were 1.67 (1.43 ~ 1.96), p < 0.001, and 1.61 (1.09 ~ 2.37), p = 0.017. Sarcopenia and hypertension were not significantly associated; the HR and 95% CI were 1.17 (0.9 ~ 1.52), p = 0.23.ConclusionThere is no significant correlation between sarcopenia and hypertension, but obesity and sarcopenic obesity increase the risk of hypertension. Targeted management of middle-aged and older people with sarcopenic obesity is needed in public health efforts.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1479169/fullobesitysarcopeniasarcopenic obesityhypertensionCHARLS |
| spellingShingle | Runfen Du Junchao Yuan Yunda Huang Guihua Jiang Zhiping Duan Hong Yang Wei Huang Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study Frontiers in Public Health obesity sarcopenia sarcopenic obesity hypertension CHARLS |
| title | Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study |
| title_full | Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study |
| title_fullStr | Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study |
| title_full_unstemmed | Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study |
| title_short | Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study |
| title_sort | sarcopenia is not associated with hypertension but sarcopenic obesity increases risk of hypertension a 7 year cohort study |
| topic | obesity sarcopenia sarcopenic obesity hypertension CHARLS |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1479169/full |
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