Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria
Infection with Herpes Simplex Virus type 2 (HSV-2) is a significant public health problem being the leading cause of genital ulcerative disease. This study was aimed to evaluate the seroprevalence of herpes simplex virus type 2 among healthy individuals in Katsina State, and to determine the socio...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Umaru Musa Yar'adua University, Katsina, Nigeria
2017-06-01
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| Series: | UMYU Journal of Microbiology Research |
| Subjects: | |
| Online Access: | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/311 |
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| Summary: | Infection with Herpes Simplex Virus type 2 (HSV-2) is a significant public health problem being the leading cause of genital ulcerative disease. This study was aimed to evaluate the seroprevalence of herpes simplex virus type 2 among healthy individuals in Katsina State, and to determine the socio demographic and risk factors associated with HSV-2 infection in the study area. A cross-sectional serological survey enrolling 113 apparently healthy individuals from six Local Government Areas of Katsina State was conducted, to evaluate HSV-2 seroprevalence. Serum samples were obtained from randomly selected subjects. Samples were analysed using Immunoglobulins G (IgG) and M (IgM) HSV-2 specific commercial enzyme-linked immunosorbent assay kits. The overall seroprevalence of HSV-2 IgG and IgM was 71.7% and 32.7% respectively. HSV-2 seroprevalence increased with age. The results obtained demonstrated a high prevalence of HSV-2 seropositivity among apparently healthy individuals. We recommend educational awareness of Herpes type 2 infections among the populace and routine testing for Herpes type 2 antibodies in hospital laboratories to prevent HSV-2 related morbidity and mortality, particularly in apparently healthy individuals.
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| ISSN: | 2616-0668 2814-1822 |