Safety profile of belatacept in a real-life setting: disproportionality analysis of the WHO pharmacovigilance database

Safety profile of belatacept in a real-life setting: disproportionality analysis of the WHO pharmacovigilance database

Abstract Background Belatacept is a co-stimulation blocker used in kidney transplant recipients to prevent allograft rejection. Unlike calcineurin inhibitors, belatacept is non-nephrotoxic and may carry a lower risk of cardiovascular and metabolic complications. However, the European Medicines Agenc...

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Bibliographic Details
Main Authors: Alexandre O. Gérard, Diane Merino, Nouha Ben Othman, Alexandre Destere, Delphine Viard, Elliot Ewig, Fanny Rocher, Antoine Sicard, Milou-Daniel Drici
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Pharmacology and Toxicology
Subjects:
Belatacept
Transplantation
Immunosuppression
Adverse drug reactions
Pharmacovigilance
Online Access:https://doi.org/10.1186/s40360-025-00972-6
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