Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s Law
Aneurysm modeling and simulation play an important role in many specialist areas in the field of medicine such as surgical education and training, clinical diagnosis and prediction, and treatment planning. Despite the considerable effort invested in developing computational fluid dynamics so far, vi...
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2024-11-01
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| Series: | Bioengineering |
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| author | Yong Wu Yongjie Yan Jiaxin Zhang Fei Wang Hao Cai Zhi Xiong Teng Zhou |
| author_facet | Yong Wu Yongjie Yan Jiaxin Zhang Fei Wang Hao Cai Zhi Xiong Teng Zhou |
| author_sort | Yong Wu |
| collection | DOAJ |
| description | Aneurysm modeling and simulation play an important role in many specialist areas in the field of medicine such as surgical education and training, clinical diagnosis and prediction, and treatment planning. Despite the considerable effort invested in developing computational fluid dynamics so far, visual simulation of blood flow dynamics in aneurysms, especially the under-explored aspect of bifurcation aneurysms, remains a challenging issue. To alleviate the situation, this study introduces a novel Smoothed Particle Hydrodynamics (SPH)-based method to model and visually simulate blood flow, bifurcation progression, and fluid–structure interaction. Firstly, this research consider blood in a vessel as a kind of incompressible fluid and model its flow dynamics using SPH; and secondly, to simulate bifurcation aneurysms at different progression stages including formation, growth, and rupture, this research models fluid particles by using aneurysm growth mechanism simulation in combination with vascular geometry simulation. The geometry incorporates an adjustable bifurcation structure based on Murray’s Law, and considers the interaction between blood flow, tissue fluid, and arterial wall resistance. Finally, this research discretizes the computation of wall shear stress using SPH and visualizes it in a novel particle-based representation. To examine the feasibility and validity of the proposed method, this research designed a series of numerical experiments and validation scenarios under varying test conditions and parameters. The experimental results based on numerical simulations demonstrate the effectiveness and efficiency of proposed method in modeling and simulating bifurcation aneurysm formation and growth. In addition, the results also indicate the feasibility of the proposed wall shear stress simulation and visualization scheme, which enriches the means of blood analysis. |
| format | Article |
| id | doaj-art-935ca29db8ab46dbac9ccb5d80a16f18 |
| institution | Kabale University |
| issn | 2306-5354 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
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| series | Bioengineering |
| spelling | doaj-art-935ca29db8ab46dbac9ccb5d80a16f182024-12-27T14:11:27ZengMDPI AGBioengineering2306-53542024-11-011112120010.3390/bioengineering11121200Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s LawYong Wu0Yongjie Yan1Jiaxin Zhang2Fei Wang3Hao Cai4Zhi Xiong5Teng Zhou6School of Economics, Guangdong University of Technology, Guangzhou 510520, ChinaGuangdong-Hong Kong-Macao Universities Joint Laboratory for Precision Prevention and Research of Eye Diseases, College of Mathematics and Computer Science, Shantou University, Shantou 515063, ChinaGuangdong-Hong Kong-Macao Universities Joint Laboratory for Precision Prevention and Research of Eye Diseases, College of Mathematics and Computer Science, Shantou University, Shantou 515063, ChinaGuangdong-Hong Kong-Macao Universities Joint Laboratory for Precision Prevention and Research of Eye Diseases, College of Mathematics and Computer Science, Shantou University, Shantou 515063, ChinaGuangdong-Hong Kong-Macao Universities Joint Laboratory for Precision Prevention and Research of Eye Diseases, College of Mathematics and Computer Science, Shantou University, Shantou 515063, ChinaGuangdong-Hong Kong-Macao Universities Joint Laboratory for Precision Prevention and Research of Eye Diseases, College of Mathematics and Computer Science, Shantou University, Shantou 515063, ChinaUniversity of Electronic Science and Technology of China, Chengdu 611731, ChinaAneurysm modeling and simulation play an important role in many specialist areas in the field of medicine such as surgical education and training, clinical diagnosis and prediction, and treatment planning. Despite the considerable effort invested in developing computational fluid dynamics so far, visual simulation of blood flow dynamics in aneurysms, especially the under-explored aspect of bifurcation aneurysms, remains a challenging issue. To alleviate the situation, this study introduces a novel Smoothed Particle Hydrodynamics (SPH)-based method to model and visually simulate blood flow, bifurcation progression, and fluid–structure interaction. Firstly, this research consider blood in a vessel as a kind of incompressible fluid and model its flow dynamics using SPH; and secondly, to simulate bifurcation aneurysms at different progression stages including formation, growth, and rupture, this research models fluid particles by using aneurysm growth mechanism simulation in combination with vascular geometry simulation. The geometry incorporates an adjustable bifurcation structure based on Murray’s Law, and considers the interaction between blood flow, tissue fluid, and arterial wall resistance. Finally, this research discretizes the computation of wall shear stress using SPH and visualizes it in a novel particle-based representation. To examine the feasibility and validity of the proposed method, this research designed a series of numerical experiments and validation scenarios under varying test conditions and parameters. The experimental results based on numerical simulations demonstrate the effectiveness and efficiency of proposed method in modeling and simulating bifurcation aneurysm formation and growth. In addition, the results also indicate the feasibility of the proposed wall shear stress simulation and visualization scheme, which enriches the means of blood analysis.https://www.mdpi.com/2306-5354/11/12/1200bifurcation aneurysm simulationsmoothed particle hydrodynamicsMurray’s Lawwall shear stress |
| spellingShingle | Yong Wu Yongjie Yan Jiaxin Zhang Fei Wang Hao Cai Zhi Xiong Teng Zhou Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s Law Bioengineering bifurcation aneurysm simulation smoothed particle hydrodynamics Murray’s Law wall shear stress |
| title | Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s Law |
| title_full | Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s Law |
| title_fullStr | Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s Law |
| title_full_unstemmed | Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s Law |
| title_short | Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray’s Law |
| title_sort | modeling and visual simulation of bifurcation aneurysms using smoothed particle hydrodynamics and murray s law |
| topic | bifurcation aneurysm simulation smoothed particle hydrodynamics Murray’s Law wall shear stress |
| url | https://www.mdpi.com/2306-5354/11/12/1200 |
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