Inhibition of MBTPS1 enhances antitumor immunity and potentiates anti-PD-1 immunotherapy
Abstract Despite advances in cancer immunotherapy, colorectal cancer patients exhibit limited therapeutic responses. Therefore, the exploration of strategies combining immunotherapy with adjuvant approaches to enhance adaptive immune responses is in demand. Here, we perform a customized in vivo CRIS...
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| Main Authors: | Yi-Yu Wang, Jin-Fei Lin, Wen-Wei Wu, Zhe Fu, Fen Cao, Yan-Xing Chen, Hai-Yu Mo, Hui Sheng, Ze-Xian Liu, Zhao-Lei Zeng, Xin-Yuan Guan, Huai-Qiang Ju, Kun Liao, Rui-Hua Xu |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59193-4 |
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