Metabolic engineering of Priestia megaterium for 2’-fucosyllactose production

Metabolic engineering of Priestia megaterium for 2’-fucosyllactose production

Abstract Background 2′-Fucosyllactose (2′-FL) is a predominant human milk oligosaccharide that significantly enhances infant nutrition and immune health. This study addresses the need for a safe and economical production of 2’-FL by employing Generally Recognized As Safe (GRAS) microbial strain, Pri...

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Bibliographic Details
Main Authors: Bu-Soo Park, Jihee Yoon, Jun-Min Lee, Sang-Hyeok Cho, Yoojeong Choi, Byung-Kwan Cho, Min-Kyu Oh
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Microbial Cell Factories
Subjects:
Metabolic engineering
2’-fucosyllactose
α-1,2-fucosyltransferase
HMO
GRAS
Priestia megaterium ATCC 14581
Online Access:https://doi.org/10.1186/s12934-024-02620-w
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