Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor Atoms
New complexes of nickel(II) and palladium(II) were synthesized using the ferrocenyl imine ligand. This Schiff base ligand was coordinated to the metal ions through the imine N and thiolic S atoms. The synthesized complexes were characterized by FT-IR, 1H NMR, UV–Vis spectroscopy and elemental analys...
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Semnan University
2024-08-01
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| Series: | شیمی کاربردی روز |
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| Online Access: | https://chemistry.semnan.ac.ir/article_8951_b15acebaa04ba3941596baccf312334b.pdf |
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| author | Mohsen Atghaei Bita Shafaatian Seyyed Ahmad Rezvani |
| author_facet | Mohsen Atghaei Bita Shafaatian Seyyed Ahmad Rezvani |
| author_sort | Mohsen Atghaei |
| collection | DOAJ |
| description | New complexes of nickel(II) and palladium(II) were synthesized using the ferrocenyl imine ligand. This Schiff base ligand was coordinated to the metal ions through the imine N and thiolic S atoms. The synthesized complexes were characterized by FT-IR, 1H NMR, UV–Vis spectroscopy and elemental analysis. The IR spectra of complexes show characteristic of imine group. Furthermore, the 1H NMR spectra display different protons of the cyclopentadienyl groups. The binding interactions of the compounds with DNA were investigated by the electronic absorption spectroscopy, and the intrinsic binding constants (Kb) were calculated for the Schiff base ligand, nickel and palladium complexes as 2.7×104, 1.2×105 and 7.2×104, respectively. The obtained data showed that the synthesized compounds bind to DNA via intercalative binding modes. Also, viscosity was investigated in order to further explore the nature of interactions between the compounds and DNA. Accordingly, it was found that the synthesized compounds bind to DNA via intercalative binding modes. |
| format | Article |
| id | doaj-art-92e49bfebe2c4ff289bee662f4a268d4 |
| institution | Kabale University |
| issn | 2981-2437 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Semnan University |
| record_format | Article |
| series | شیمی کاربردی روز |
| spelling | doaj-art-92e49bfebe2c4ff289bee662f4a268d42024-12-09T08:30:31ZengSemnan Universityشیمی کاربردی روز2981-24372024-08-01197218920410.22075/chem.2024.31723.22128951Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor AtomsMohsen Atghaei0Bita Shafaatian1Seyyed Ahmad Rezvani2Faculty of Chemistry, Department of Inorganic Chemistry, Damghan University, Damghan, IranFaculty of Chemistry, Department of Inorganic Chemistry, Damghan University, Damghan, IranFaculty of Chemistry, Department of Analytical Chemistry, Damghan University, Damghan, IranNew complexes of nickel(II) and palladium(II) were synthesized using the ferrocenyl imine ligand. This Schiff base ligand was coordinated to the metal ions through the imine N and thiolic S atoms. The synthesized complexes were characterized by FT-IR, 1H NMR, UV–Vis spectroscopy and elemental analysis. The IR spectra of complexes show characteristic of imine group. Furthermore, the 1H NMR spectra display different protons of the cyclopentadienyl groups. The binding interactions of the compounds with DNA were investigated by the electronic absorption spectroscopy, and the intrinsic binding constants (Kb) were calculated for the Schiff base ligand, nickel and palladium complexes as 2.7×104, 1.2×105 and 7.2×104, respectively. The obtained data showed that the synthesized compounds bind to DNA via intercalative binding modes. Also, viscosity was investigated in order to further explore the nature of interactions between the compounds and DNA. Accordingly, it was found that the synthesized compounds bind to DNA via intercalative binding modes.https://chemistry.semnan.ac.ir/article_8951_b15acebaa04ba3941596baccf312334b.pdfdna interactionbinding constantferroceneschiff basepalladium complexnickel complex |
| spellingShingle | Mohsen Atghaei Bita Shafaatian Seyyed Ahmad Rezvani Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor Atoms شیمی کاربردی روز dna interaction binding constant ferrocene schiff base palladium complex nickel complex |
| title | Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor Atoms |
| title_full | Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor Atoms |
| title_fullStr | Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor Atoms |
| title_full_unstemmed | Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor Atoms |
| title_short | Investigation of Interaction of CT-DNA with New Nickel and Palladium Complexes Containing Ferrocene Group with N and S Donor Atoms |
| title_sort | investigation of interaction of ct dna with new nickel and palladium complexes containing ferrocene group with n and s donor atoms |
| topic | dna interaction binding constant ferrocene schiff base palladium complex nickel complex |
| url | https://chemistry.semnan.ac.ir/article_8951_b15acebaa04ba3941596baccf312334b.pdf |
| work_keys_str_mv | AT mohsenatghaei investigationofinteractionofctdnawithnewnickelandpalladiumcomplexescontainingferrocenegroupwithnandsdonoratoms AT bitashafaatian investigationofinteractionofctdnawithnewnickelandpalladiumcomplexescontainingferrocenegroupwithnandsdonoratoms AT seyyedahmadrezvani investigationofinteractionofctdnawithnewnickelandpalladiumcomplexescontainingferrocenegroupwithnandsdonoratoms |