Inter- and intra-tumoral heterogeneity on [68Ga]Ga-DOTA-TATE/[68Ga]Ga-DOTA-TOC PET/CT predicts response to [177Lu]Lu-DOTA-TATE PRRT in neuroendocrine tumor patients

Inter- and intra-tumoral heterogeneity on [68Ga]Ga-DOTA-TATE/[68Ga]Ga-DOTA-TOC PET/CT predicts response to [177Lu]Lu-DOTA-TATE PRRT in neuroendocrine tumor patients

Abstract Background Indices of tumor heterogeneity on somatostatin receptor PET/CT scans may potentially serve as predictive biomarkers of treatment efficacy in neuroendocrine tumor (NET) patients undergoing [177Lu]Lu-DOTA-TATE PRRT. Methods NET patients who underwent [177Lu]Lu-DOTA-TATE therapy at...

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Main Authors: Camila Gadens Zamboni, Ayca Dundar, Sanchay Jain, Marc Kruzer, Bradley T. Loeffler, Stephen A. Graves, Janet H. Pollard, Sarah L. Mott, Joseph S. Dillon, Michael M. Graham, Yusuf Menda, Ahmad Shariftabrizi
Format: Article
Language:English
Published: Springer 2024-11-01
Series:EJNMMI Reports
Online Access:https://doi.org/10.1186/s41824-024-00227-3
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