The integrin repertoire drives YAP-dependent epithelial:stromal interactions during injury of the kidney glomerulus

The integrin repertoire drives YAP-dependent epithelial:stromal interactions during injury of the kidney glomerulus

Abstract The kidney glomerulus is a filtration barrier in which capillary loop architecture depends on epithelial-stromal interactions between podocytes and mesangial cells. Podocytes are terminally differentiated cells within the glomerulus that express YAP and TAZ. Here we test the hypotheses that...

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Main Authors: Evelyne Huynh-Cong, Victoria Driscoll, Sandrine Ettou, Keith Keller, Amha Atakilit, Mary E. Taglienti, Saurabh Kumar, Astrid Weins, Valerie A. Schumacher, Jordan A. Kreidberg
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58567-y
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