Identification of barley yellow dwarf virus strains and genetic analysis of GAV strains in Qinghai Province

Barley yellow dwarf disease, caused by barley yellow dwarf virus (BYDVs), significantly affects global wheat crop production. It has reached epidemic proportions in the Qinghai Province, China. To explore the primary epidemic strains, genetic evolution, and molecular characteristics of the disease,...

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Bibliographic Details
Main Authors: Xiaoyang Wang, Qin Shu, Shiying Qiao, Hua Weng, Jiahui Yan
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:All Life
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Online Access:http://dx.doi.org/10.1080/26895293.2024.2446250
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Summary:Barley yellow dwarf disease, caused by barley yellow dwarf virus (BYDVs), significantly affects global wheat crop production. It has reached epidemic proportions in the Qinghai Province, China. To explore the primary epidemic strains, genetic evolution, and molecular characteristics of the disease, 90 samples were collected from various locations in Qinghai Province between July and September 2019. Molecular identification and genetic analysis identified BYDV-GAV as the predominant strain in Qinghai Province, with a detection rate of 92%. We successfully cloned 44 BYDV-GAV isolates with genome lengths of approximately 5.7 kb. Molecular population genetics analysis indicated low genetic divergence (genetic distance <0.1) among the geographical populations of BYDV-GAV in Qinghai Province. The low FST values (<0.33) and high Nm values (2.65–6.21) suggested significant gene flow and reduced genetic differentiation between isolates. Tajima’s D value was negative, and the dN/dS value of the CP gene exceeded 1, indicating non-synonymous mutations, positive selection pressure, or diversified selection in the BYDV-GAV isolates from Qinghai Province. Phylogenetic analysis revealed nine distinct groups with a sequence similarity of 99% among the BYDV-GAV isolates, suggesting a common ancestral origin. These findings imply the relative stability of the disease in the Qinghai Province.
ISSN:2689-5307