Glial cells improve Parkinson’s disease by modulating neuronal function and regulating neuronal ferroptosis

Glial cells improve Parkinson’s disease by modulating neuronal function and regulating neuronal ferroptosis

The main characteristics of Parkinson’s disease (PD) are the loss of dopaminergic (DA) neurons and abnormal aggregation of cytosolic proteins. However, the exact pathogenesis of PD remains unclear, with ferroptosis emerging as one of the key factors driven by iron accumulation and lipid peroxidation...

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Bibliographic Details
Main Authors: Mengzhu Li, Mengxuan Chen, Haiyan Li, Da Gao, Lijun Zhao, Meiling Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Parkinson’s disease
ferroptosis
glia-neuron interaction
dopaminergic neuron
glial cell
microglia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1510897/full
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