Berberine alleviates chronic pain-induced anxiety-like behaviors by inhibiting the activation of VLT-projecting cACC (Cg2) neurons

Berberine alleviates chronic pain-induced anxiety-like behaviors by inhibiting the activation of VLT-projecting cACC (Cg2) neurons

Abstract Chronic pain is often accompanied by anxiety, and gradually increasing anxiety makes the pain itself more protracted. Berberine has been found to be able to cross the blood–brain barrier to treat psychiatric disorders, but its neurocirculatory mechanisms remain unclear. Here, we found that...

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Bibliographic Details
Main Authors: Min He, Ye-Xiang Chen, Pei-Pei Feng, Jie Chen, Chi Xu, Shu-Ting Zhou, Bo-Yu Liu, Xiao-Fen He, Xiao-Mei Shao, Jian-Qiao Fang, Zui Shen, Jing-Gen Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07372-2
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