Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response
Virus-like particles (VLPs), as a unique form of nanocarrier, predominantly encompass hollow protein shells that exhibit analogous morphology and structure to naturally occurring viruses, yet devoid of genetic material. VLPs are considered safe, easily modifiable, and stable, making them suitable fo...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1504124/full |
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| author | Weisen Ning Sheng Yan Yongyao Song Hanning Xu Jinling Zhang Xiaomei Wang |
| author_facet | Weisen Ning Sheng Yan Yongyao Song Hanning Xu Jinling Zhang Xiaomei Wang |
| author_sort | Weisen Ning |
| collection | DOAJ |
| description | Virus-like particles (VLPs), as a unique form of nanocarrier, predominantly encompass hollow protein shells that exhibit analogous morphology and structure to naturally occurring viruses, yet devoid of genetic material. VLPs are considered safe, easily modifiable, and stable, making them suitable for preparation in various expression systems. They serve as precise biological instruments with broad applications in the field of medical biology. Leveraging their unique structural attributes and facile modification capabilities, VLPs can serve as an effective platform for the delivery of tumor antigens, thereby stimulating the immune system and facilitating the eradication of tumor cells. |
| format | Article |
| id | doaj-art-921c42490c3c4c1e90ad61684cc62fab |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-921c42490c3c4c1e90ad61684cc62fab2025-01-07T06:45:30ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-01-011510.3389/fimmu.2024.15041241504124Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune responseWeisen Ning0Sheng Yan1Yongyao Song2Hanning Xu3Jinling Zhang4Xiaomei Wang5School of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, ChinaSchool of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, ChinaSchool of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, ChinaSchool of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Oncology, Wuhan Fourth Hospital, Wuhan Orthopedic Hospital, Wuhan, Hubei, ChinaSchool of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, ChinaVirus-like particles (VLPs), as a unique form of nanocarrier, predominantly encompass hollow protein shells that exhibit analogous morphology and structure to naturally occurring viruses, yet devoid of genetic material. VLPs are considered safe, easily modifiable, and stable, making them suitable for preparation in various expression systems. They serve as precise biological instruments with broad applications in the field of medical biology. Leveraging their unique structural attributes and facile modification capabilities, VLPs can serve as an effective platform for the delivery of tumor antigens, thereby stimulating the immune system and facilitating the eradication of tumor cells.https://www.frontiersin.org/articles/10.3389/fimmu.2024.1504124/fullvirus-like particlestumor immunotherapytumor vaccinetumor antigensnanoplatform |
| spellingShingle | Weisen Ning Sheng Yan Yongyao Song Hanning Xu Jinling Zhang Xiaomei Wang Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response Frontiers in Immunology virus-like particles tumor immunotherapy tumor vaccine tumor antigens nanoplatform |
| title | Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response |
| title_full | Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response |
| title_fullStr | Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response |
| title_full_unstemmed | Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response |
| title_short | Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response |
| title_sort | virus like particle a nano platform that delivers cancer antigens to elicit an anti tumor immune response |
| topic | virus-like particles tumor immunotherapy tumor vaccine tumor antigens nanoplatform |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1504124/full |
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