α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments

α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments

Abstract Post-translational cycles of α-tubulin detyrosination and tyrosination generate microtubule diversity, the cellular functions of which remain largely unknown. Here we show that α-tubulin detyrosination regulates kinetochore-microtubule attachments to ensure normal chromosome oscillations an...

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Main Authors: Hugo Girão, Joana Macário-Monteiro, Ana C. Figueiredo, Ricardo Silva e Sousa, Elena Doria, Vladimir Demidov, Hugo Osório, Ariana Jacome, Patrick Meraldi, Ekaterina L. Grishchuk, Helder Maiato
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54155-8
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https://doi.org/10.1038/s41467-024-54155-8

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