The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint
PurposeThe Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository is a collaboration established in 2024 by seven stroke centres in Europe. MAGIC consolidates clinical and radiological data from acute ischemic stroke (AIS) patients who underwent endovascular therapy, intraven...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Neuroinformatics |
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| author | Hakim Baazaoui Stefan T. Engelter Stefan T. Engelter Stefan T. Engelter Henrik Gensicke Henrik Gensicke Henrik Gensicke Lukas S. Enz Lukas S. Enz Marios Psychogios Marios Psychogios Matthias Mutke Matthias Mutke Patrik Michel Davide Strambo Alexander Salerno Henk A. Marquering Paul J. Nederkoorn Nabila Wali Stephanie Tanadini-Lang Björn Menze Ezequiel de la Rosa Kaiyuan Yang Gian Marco De Marchis Gian Marco De Marchis Tolga D. Dittrich Tolga D. Dittrich Francesco Valletta Francesco Valletta Manon Germann Carlo W. Cereda João Pedro Marto Lisa Herzog Patrick Hirschi Zsolt Kulcsar Susanne Wegener Susanne Wegener |
| author_facet | Hakim Baazaoui Stefan T. Engelter Stefan T. Engelter Stefan T. Engelter Henrik Gensicke Henrik Gensicke Henrik Gensicke Lukas S. Enz Lukas S. Enz Marios Psychogios Marios Psychogios Matthias Mutke Matthias Mutke Patrik Michel Davide Strambo Alexander Salerno Henk A. Marquering Paul J. Nederkoorn Nabila Wali Stephanie Tanadini-Lang Björn Menze Ezequiel de la Rosa Kaiyuan Yang Gian Marco De Marchis Gian Marco De Marchis Tolga D. Dittrich Tolga D. Dittrich Francesco Valletta Francesco Valletta Manon Germann Carlo W. Cereda João Pedro Marto Lisa Herzog Patrick Hirschi Zsolt Kulcsar Susanne Wegener Susanne Wegener |
| author_sort | Hakim Baazaoui |
| collection | DOAJ |
| description | PurposeThe Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository is a collaboration established in 2024 by seven stroke centres in Europe. MAGIC consolidates clinical and radiological data from acute ischemic stroke (AIS) patients who underwent endovascular therapy, intravenous thrombolysis, a combination of both, or conservative management.ParticipantsAll centres ensure accuracy and completeness of the data. Only patients who did not refuse use of their routine data collected during or after their hospital stay are included in the repository. Approvals or waivers are obtained from the responsible ethics committees before data exchange. A formal data transfer agreement (DTA) is signed by all contributing centres. The centres then share their data, and files are stored centrally on a safe server at the University Hospital Zurich. There, patient identifiers are removed and images are algorithmically de-faced. De-identified structured clinical data are connected to the imaging data by a new identifier. Data are made available to participating centres which have entered into a DTA for stroke research projects.Repository setupInitially, MAGIC is set to comprise initial and first follow-up imaging of 2,500 AIS patients. Clinical data consist of a comprehensive set of patient characteristics and routine prehospital metrics, treatment and laboratory variables.OutlookOur repository will support research by leveraging the entire range of routinely collected imaging and clinical data. This dataset reflects the current state of practice in stroke patient evaluation and management and will enable researchers to retrospectively study clinically relevant questions outside the scope of randomized controlled clinical trials. New centres are invited to join MAGIC if they meet the requirements outlined here. We aim to reach approximately 10,000 cases by 2026. |
| format | Article |
| id | doaj-art-91e097eed8514c3ab7f06aa0b10be794 |
| institution | Kabale University |
| issn | 1662-5196 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroinformatics |
| spelling | doaj-art-91e097eed8514c3ab7f06aa0b10be7942025-01-07T06:45:02ZengFrontiers Media S.A.Frontiers in Neuroinformatics1662-51962025-01-011810.3389/fninf.2024.15081611508161The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprintHakim Baazaoui0Stefan T. Engelter1Stefan T. Engelter2Stefan T. Engelter3Henrik Gensicke4Henrik Gensicke5Henrik Gensicke6Lukas S. Enz7Lukas S. Enz8Marios Psychogios9Marios Psychogios10Matthias Mutke11Matthias Mutke12Patrik Michel13Davide Strambo14Alexander Salerno15Henk A. Marquering16Paul J. Nederkoorn17Nabila Wali18Stephanie Tanadini-Lang19Björn Menze20Ezequiel de la Rosa21Kaiyuan Yang22Gian Marco De Marchis23Gian Marco De Marchis24Tolga D. Dittrich25Tolga D. Dittrich26Francesco Valletta27Francesco Valletta28Manon Germann29Carlo W. Cereda30João Pedro Marto31Lisa Herzog32Patrick Hirschi33Zsolt Kulcsar34Susanne Wegener35Susanne Wegener36Department of Neurology, University Hospital Zurich, Zurich, SwitzerlandNeurorehabilitation and Neurology, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, SwitzerlandDepartment of Neurology and Stroke Center, University of Basel and University Hospital Basel, Basel, SwitzerlandDepartment of Clinical Research, University of Basel, Basel, SwitzerlandNeurorehabilitation and Neurology, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, SwitzerlandDepartment of Neurology and Stroke Center, University of Basel and University Hospital Basel, Basel, SwitzerlandDepartment of Clinical Research, University of Basel, Basel, SwitzerlandDepartment of Neurology and Stroke Center, University of Basel and University Hospital Basel, Basel, SwitzerlandDepartment of Clinical Research, University of Basel, Basel, SwitzerlandDepartment of Clinical Research, University of Basel, Basel, SwitzerlandDepartment of Neuroradiology, University Hospital Basel, Basel, SwitzerlandDepartment of Clinical Research, University of Basel, Basel, SwitzerlandDepartment of Neuroradiology, University Hospital Basel, Basel, SwitzerlandStroke Center, Neurology Service, Department of Neurological Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, SwitzerlandStroke Center, Neurology Service, Department of Neurological Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, SwitzerlandStroke Center, Neurology Service, Department of Neurological Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, SwitzerlandRadiology and Nuclear Medicine/Biomedical Engineering and Physics, Amsterdam University Medical Centers, Amsterdam, NetherlandsDepartment of Neurology, Amsterdam University Medical Centers, Amsterdam, NetherlandsDepartment of Neurology, Amsterdam University Medical Centers, Amsterdam, NetherlandsDepartment of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland0Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland0Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland0Department of Quantitative Biomedicine, University of Zurich, Zurich, SwitzerlandDepartment of Clinical Research, University of Basel, Basel, Switzerland1Department of Neurology and Stroke Center, Cantonal Hospital St. Gallen, St. Gallen, SwitzerlandDepartment of Clinical Research, University of Basel, Basel, Switzerland1Department of Neurology and Stroke Center, Cantonal Hospital St. Gallen, St. Gallen, Switzerland1Department of Neurology and Stroke Center, Cantonal Hospital St. Gallen, St. Gallen, Switzerland2DAI di Neuroscienze, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy3Department of Radiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland4Stroke Center EOC, Neurocenter of Southern Switzerland, Lugano, Switzerland5Department of Neurology, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, PortugalDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland6Clinical Data Platform for Research, University Hospital Zurich, Zurich, Switzerland7Department of Neuroradiology, University Hospital Zurich, Zurich, SwitzerlandDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland8Neuroscience Center Zurich, University of Zurich and ETH, Zurich, SwitzerlandPurposeThe Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository is a collaboration established in 2024 by seven stroke centres in Europe. MAGIC consolidates clinical and radiological data from acute ischemic stroke (AIS) patients who underwent endovascular therapy, intravenous thrombolysis, a combination of both, or conservative management.ParticipantsAll centres ensure accuracy and completeness of the data. Only patients who did not refuse use of their routine data collected during or after their hospital stay are included in the repository. Approvals or waivers are obtained from the responsible ethics committees before data exchange. A formal data transfer agreement (DTA) is signed by all contributing centres. The centres then share their data, and files are stored centrally on a safe server at the University Hospital Zurich. There, patient identifiers are removed and images are algorithmically de-faced. De-identified structured clinical data are connected to the imaging data by a new identifier. Data are made available to participating centres which have entered into a DTA for stroke research projects.Repository setupInitially, MAGIC is set to comprise initial and first follow-up imaging of 2,500 AIS patients. Clinical data consist of a comprehensive set of patient characteristics and routine prehospital metrics, treatment and laboratory variables.OutlookOur repository will support research by leveraging the entire range of routinely collected imaging and clinical data. This dataset reflects the current state of practice in stroke patient evaluation and management and will enable researchers to retrospectively study clinically relevant questions outside the scope of randomized controlled clinical trials. New centres are invited to join MAGIC if they meet the requirements outlined here. We aim to reach approximately 10,000 cases by 2026.https://www.frontiersin.org/articles/10.3389/fninf.2024.1508161/fullischemic strokeneuroimagingdata sharingneurologycollaborationrepository |
| spellingShingle | Hakim Baazaoui Stefan T. Engelter Stefan T. Engelter Stefan T. Engelter Henrik Gensicke Henrik Gensicke Henrik Gensicke Lukas S. Enz Lukas S. Enz Marios Psychogios Marios Psychogios Matthias Mutke Matthias Mutke Patrik Michel Davide Strambo Alexander Salerno Henk A. Marquering Paul J. Nederkoorn Nabila Wali Stephanie Tanadini-Lang Björn Menze Ezequiel de la Rosa Kaiyuan Yang Gian Marco De Marchis Gian Marco De Marchis Tolga D. Dittrich Tolga D. Dittrich Francesco Valletta Francesco Valletta Manon Germann Carlo W. Cereda João Pedro Marto Lisa Herzog Patrick Hirschi Zsolt Kulcsar Susanne Wegener Susanne Wegener The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint Frontiers in Neuroinformatics ischemic stroke neuroimaging data sharing neurology collaboration repository |
| title | The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint |
| title_full | The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint |
| title_fullStr | The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint |
| title_full_unstemmed | The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint |
| title_short | The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint |
| title_sort | multicentre acute ischemic stroke imaging and clinical data magic repository rationale and blueprint |
| topic | ischemic stroke neuroimaging data sharing neurology collaboration repository |
| url | https://www.frontiersin.org/articles/10.3389/fninf.2024.1508161/full |
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