The Cellular and Transcriptomic Early Innate Immune Response to BCG Vaccination in Mice

The Cellular and Transcriptomic Early Innate Immune Response to BCG Vaccination in Mice

It is established that BCG vaccination results in the development of both a specific immune response to mycobacterial infections and a nonspecific (heterologous) immune response, designated as trained immunity (TRIM), to other pathogens. We hypothesized that local BCG immunization may induce an earl...

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Bibliographic Details
Main Authors: Liya G. Kondratyeva, Olga A. Rakitina, Victor V. Pleshkan, Alexey I. Kuzmich, Irina A. Linge, Sofia A. Kondratieva, Eugene V. Snezhkov, Irina V. Alekseenko, Eugene D. Sverdlov
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
trained immunity
BCG
innate immunity
vaccination
transcriptome
RNA-seq
Online Access:https://www.mdpi.com/2073-4409/13/24/2043
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