Post sleeve gastrectomy-enriched gut commensal Clostridia promotes secondary bile acid increase and weight loss

Post sleeve gastrectomy-enriched gut commensal Clostridia promotes secondary bile acid increase and weight loss

The gut microbiome is altered after bariatric surgery and is associated with weight loss. However, the commensal bacteria involved and the underlying mechanism remain to be determined. We performed shotgun metagenomic sequencing in obese subjects before and longitudinally after sleeve gastrectomy (S...

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Main Authors: Shaoqian Zhao, Huibin Lin, Wen Li, Xiaoqiang Xu, Qihan Wu, Zhifeng Wang, Juan Shi, Yufei Chen, Lingxia Ye, Liuqing Xi, Lijia Chen, Mingyang Yuan, Junlei Su, Aibo Gao, Jiabin Jin, Xiayang Ying, Xiaolin Wang, Yaorui Ye, Yingkai Sun, Yifei Zhang, Xiaxing Deng, Baiyong Shen, Weiqiong Gu, Guang Ning, Weiqing Wang, Jie Hong, Jiqiu Wang, Ruixin Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Obesity
sleeve gastrectomy
Clostridia
bile acids
TGR5
lipolysis
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2462261
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