Super-enhancer-driven SLCO4A1-AS1 is a new biomarker and a promising therapeutic target in glioblastoma

Super-enhancer-driven SLCO4A1-AS1 is a new biomarker and a promising therapeutic target in glioblastoma

Abstract Glioblastoma (GBM) is the most common intracranial malignancy, but current treatment options are limited. Super-enhancers (SEs) have been found to drive the expression of key oncogenes in GBM. However, the role of SE-associated long non-coding RNAs (lncRNAs) in GBM remains poorly understood...

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Bibliographic Details
Main Authors: Yibo Wu, Fang Li, Chen Yang, Xuehai Zhang, Zhiwei Xue, Yanfei Sun, Xiaoying Lin, Xuemeng Liu, Zhimin Zhao, Bin Huang, Qibing Huang, Xingang Li, Mingzhi Han
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
GBM
Super-enhancer
SLCO4A1-AS1
Long non-coding RNAs
VX-11e
Online Access:https://doi.org/10.1038/s41598-024-82109-z
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