The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) Methodology

Photonic therapy is emerging as a promising method in neuroscience for addressing Alzheimer’s disease (AD). This study uses computational simulations to investigate the impact of specific wavelengths emitted by photodiodes on the light absorption rates in brain tissue for brain implant sensors. Addi...

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Main Authors: So-Hyun Cho, Chang-Hee Won, Chang-Hyun Kim, Jong-Ha Lee
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Sensors
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Online Access:https://www.mdpi.com/1424-8220/24/22/7282
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author So-Hyun Cho
Chang-Hee Won
Chang-Hyun Kim
Jong-Ha Lee
author_facet So-Hyun Cho
Chang-Hee Won
Chang-Hyun Kim
Jong-Ha Lee
author_sort So-Hyun Cho
collection DOAJ
description Photonic therapy is emerging as a promising method in neuroscience for addressing Alzheimer’s disease (AD). This study uses computational simulations to investigate the impact of specific wavelengths emitted by photodiodes on the light absorption rates in brain tissue for brain implant sensors. Additionally, it presents a novel methodology that enhances light absorption via multi-parameter optimization. By adjusting the angle and wavelength of the incident light, the absorption rate was significantly enhanced using four photodiodes, each emitting at 660 nm with a power input of 3 mW. Notably, an incident angle of 20 degrees optimized light absorption and minimized thermal effects on brain tissue. The findings indicate that photodiodes within the near-infrared spectrum are suitable for low-temperature therapeutic applications in brain tissues, affirming the viability of non-invasive and safe photonic therapy. This research contributes foundational data for advancing brain implant photonic sensor design and therapeutic strategies. Furthermore, it establishes conditions for achieving high light absorption rates with minimal heat generation, identifying optimal parameters for efficient energy transfer.
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id doaj-art-9145f0f6e1c24f828d3f3fd94217f5ca
institution Kabale University
issn 1424-8220
language English
publishDate 2024-11-01
publisher MDPI AG
record_format Article
series Sensors
spelling doaj-art-9145f0f6e1c24f828d3f3fd94217f5ca2024-11-26T18:21:22ZengMDPI AGSensors1424-82202024-11-012422728210.3390/s24227282The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) MethodologySo-Hyun Cho0Chang-Hee Won1Chang-Hyun Kim2Jong-Ha Lee3Department of Biomedical Engineering, School of Engineering, Keimyung University, Daegu 42601, Republic of KoreaDepartment of Electrical Engineering, School of Engineering, Temple University, Philadelphia, PA 19122, USADepartment of Neurosurgery, Keimyung University Dongsan Hospital, Daegu 42601, Republic of KoreaDepartment of Biomedical Engineering, School of Engineering, Keimyung University, Daegu 42601, Republic of KoreaPhotonic therapy is emerging as a promising method in neuroscience for addressing Alzheimer’s disease (AD). This study uses computational simulations to investigate the impact of specific wavelengths emitted by photodiodes on the light absorption rates in brain tissue for brain implant sensors. Additionally, it presents a novel methodology that enhances light absorption via multi-parameter optimization. By adjusting the angle and wavelength of the incident light, the absorption rate was significantly enhanced using four photodiodes, each emitting at 660 nm with a power input of 3 mW. Notably, an incident angle of 20 degrees optimized light absorption and minimized thermal effects on brain tissue. The findings indicate that photodiodes within the near-infrared spectrum are suitable for low-temperature therapeutic applications in brain tissues, affirming the viability of non-invasive and safe photonic therapy. This research contributes foundational data for advancing brain implant photonic sensor design and therapeutic strategies. Furthermore, it establishes conditions for achieving high light absorption rates with minimal heat generation, identifying optimal parameters for efficient energy transfer.https://www.mdpi.com/1424-8220/24/22/7282Alzheimer sensorcomputational simulationlight absorptionphototherapy optimizationtherapeutic light angle
spellingShingle So-Hyun Cho
Chang-Hee Won
Chang-Hyun Kim
Jong-Ha Lee
The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) Methodology
Sensors
Alzheimer sensor
computational simulation
light absorption
phototherapy optimization
therapeutic light angle
title The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) Methodology
title_full The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) Methodology
title_fullStr The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) Methodology
title_full_unstemmed The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) Methodology
title_short The Optical Parameter Optimization for Brain Implant Alzheimer Sensor Using Phototherapy Angle and Wavelength Simulation (PAWS) Methodology
title_sort optical parameter optimization for brain implant alzheimer sensor using phototherapy angle and wavelength simulation paws methodology
topic Alzheimer sensor
computational simulation
light absorption
phototherapy optimization
therapeutic light angle
url https://www.mdpi.com/1424-8220/24/22/7282
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