Celastrol boosts fluconazole efficacy against vaginal candidiasis: in vitro and in vivo evidence
Abstract Candida albicans is a commensal fungus that naturally inhabits the vagina. However, overgrowth of C. albicans can result in vulvovaginal candidiasis (VVC), one of the most prevalent fungal infections affecting women. The rapid emergence of azole resistance in C. albicans, in addition to the...
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Main Authors: | Fatma Al-zahraa A. Yehia, Hisham A Abbas, Tarek M. Ibrahim, Basem Mansour, Zuhier A. Awan, Mohammed W. Al-Rabia, Wesam H. Abdulaal, Mustafa Adnan Zeyadi, Solomon Z. Okbazghi, Tarek S. Ibrahim, Wael A. H. Hegazy, Salwa E. Gomaa |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2025-01-01
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Series: | AMB Express |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13568-025-01824-6 |
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