Psychiatric presentation in Rasmussen’s encephalitis
Rasmussen’s encephalitis (RE) is a rare neurological disorder characterized by drug-resistant focal epilepsy, progressive hemiplegia, and cognitive decline. While the neurological aspects of RE have been extensively studied, its psychiatric manifestations are often overlooked. This case series prese...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Industrial Psychiatry Journal |
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| Online Access: | https://journals.lww.com/10.4103/ipj.ipj_121_24 |
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| author | Prashant Maravi Suneel Singh Kushwaha Riya Gangwal Dheerendra Mishra Nimisha Mishra |
| author_facet | Prashant Maravi Suneel Singh Kushwaha Riya Gangwal Dheerendra Mishra Nimisha Mishra |
| author_sort | Prashant Maravi |
| collection | DOAJ |
| description | Rasmussen’s encephalitis (RE) is a rare neurological disorder characterized by drug-resistant focal epilepsy, progressive hemiplegia, and cognitive decline. While the neurological aspects of RE have been extensively studied, its psychiatric manifestations are often overlooked. This case series presents four illustrative cases of RE with prominent psychiatric symptoms. All cases exhibited a combination of longstanding seizures, developmental delays, and recent-onset psychiatric symptoms, including behavioral disturbances, psychotic features, and altered behavior. Neurological examination revealed characteristic findings such as weakness, tremors, and abnormal reflexes, alongside magnetic resonance imaging evidence of hemicerebral atrophy consistent with RE. Treatment involved a multidisciplinary approach including antiepileptic drugs, antipsychotics, and immunomodulatory therapy. Significant improvements were observed in seizure control and psychiatric symptoms following treatment. Psychiatric manifestations in RE are often attributed to seizure activity and immune responses. RE presents a complex clinical picture with both neurological and psychiatric manifestations. This case series highlights the importance of recognizing and managing psychiatric symptoms in RE to provide comprehensive care to affected individuals. |
| format | Article |
| id | doaj-art-911e033c33814db1aa8b591a40033f20 |
| institution | Kabale University |
| issn | 0972-6748 0976-2795 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Industrial Psychiatry Journal |
| spelling | doaj-art-911e033c33814db1aa8b591a40033f202025-01-07T06:45:15ZengWolters Kluwer Medknow PublicationsIndustrial Psychiatry Journal0972-67480976-27952024-12-0133240140510.4103/ipj.ipj_121_24Psychiatric presentation in Rasmussen’s encephalitisPrashant MaraviSuneel Singh KushwahaRiya GangwalDheerendra MishraNimisha MishraRasmussen’s encephalitis (RE) is a rare neurological disorder characterized by drug-resistant focal epilepsy, progressive hemiplegia, and cognitive decline. While the neurological aspects of RE have been extensively studied, its psychiatric manifestations are often overlooked. This case series presents four illustrative cases of RE with prominent psychiatric symptoms. All cases exhibited a combination of longstanding seizures, developmental delays, and recent-onset psychiatric symptoms, including behavioral disturbances, psychotic features, and altered behavior. Neurological examination revealed characteristic findings such as weakness, tremors, and abnormal reflexes, alongside magnetic resonance imaging evidence of hemicerebral atrophy consistent with RE. Treatment involved a multidisciplinary approach including antiepileptic drugs, antipsychotics, and immunomodulatory therapy. Significant improvements were observed in seizure control and psychiatric symptoms following treatment. Psychiatric manifestations in RE are often attributed to seizure activity and immune responses. RE presents a complex clinical picture with both neurological and psychiatric manifestations. This case series highlights the importance of recognizing and managing psychiatric symptoms in RE to provide comprehensive care to affected individuals.https://journals.lww.com/10.4103/ipj.ipj_121_24neuropsychiatric comorbiditiespsychiatric manifestationsrasmussen’s encephalitis |
| spellingShingle | Prashant Maravi Suneel Singh Kushwaha Riya Gangwal Dheerendra Mishra Nimisha Mishra Psychiatric presentation in Rasmussen’s encephalitis Industrial Psychiatry Journal neuropsychiatric comorbidities psychiatric manifestations rasmussen’s encephalitis |
| title | Psychiatric presentation in Rasmussen’s encephalitis |
| title_full | Psychiatric presentation in Rasmussen’s encephalitis |
| title_fullStr | Psychiatric presentation in Rasmussen’s encephalitis |
| title_full_unstemmed | Psychiatric presentation in Rasmussen’s encephalitis |
| title_short | Psychiatric presentation in Rasmussen’s encephalitis |
| title_sort | psychiatric presentation in rasmussen s encephalitis |
| topic | neuropsychiatric comorbidities psychiatric manifestations rasmussen’s encephalitis |
| url | https://journals.lww.com/10.4103/ipj.ipj_121_24 |
| work_keys_str_mv | AT prashantmaravi psychiatricpresentationinrasmussensencephalitis AT suneelsinghkushwaha psychiatricpresentationinrasmussensencephalitis AT riyagangwal psychiatricpresentationinrasmussensencephalitis AT dheerendramishra psychiatricpresentationinrasmussensencephalitis AT nimishamishra psychiatricpresentationinrasmussensencephalitis |