The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review

The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review

Abstract Despite significant advances in HIV treatment, a definitive cure remains elusive. The first-in-human clinical trial of Excision BioTherapeutics’ CRISPR-based HIV cure, EBT-101, demonstrated safety but failed to prevent viral rebound. These outcomes may result from the interplay of several f...

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Bibliographic Details
Main Authors: Punitha Letchumanan, Kumitaa Theva Das
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Epigenetics & Chromatin
Subjects:
HIV
Genetic
Epigenetic
Chromatin
Gender
ART
Online Access:https://doi.org/10.1186/s13072-024-00564-4
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