HLA-transgenic mouse models to study autoimmune central nervous system diseases

HLA-transgenic mouse models to study autoimmune central nervous system diseases

It is known that certain human leukocyte antigen (HLA) genes are associated with autoimmune central nervous system (CNS) diseases, such as multiple sclerosis (MS), but their exact role in disease susceptibility and etiopathogenesis remains unclear. The best studied HLA-associated autoimmune CNS dise...

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Bibliographic Details
Main Authors: Kyle R. Pressley, Lance Schwegman, Maria Montes De Oca Arena, Carol Chase Huizar, Scott S. Zamvil, Thomas G. Forsthuber
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autoimmunity
Subjects:
HLA
transgenic
animal model
neuroinflammation
Multiple sclerosis
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2387414
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